Not exact matches
Despite the presumed virulence of the strain — experiments with
mouse lungs showed it produces 1000 times more bacteria in
infected cells than do standard varieties — Valway says the number of TB cases that developed were kept in line with other typical outbreaks, which «shows that doing good contact investigations is important and preventative therapy works.»
When the researchers examined
mice with disrupted IL - 27 function, they found that they were more likely than normal
mice likely to die when
infected with the virus, and that they died as a consequence of rampant
lung inflammation.
When given to
infected mice, LCA60 dramatically reduced the amount of the MERS virus in the
lungs within days.
However, Feske and his colleagues found that calcium signals also are required for the development of iTreg cells and that their numbers are strongly reduced in the
lungs of the
infected STIM1 - deficient
mice.
«This was associated with an unexpected accumulation of T - cells in the
lungs of
infected mice that lack STIM1.»
In addition, low levels of PD1 in the
lungs of influenza - virus -
infected mice were associated with severe infection and highly pathogenic viruses, such as H5N1.
When
infected with TB,
mice lacking Smurf1 had higher bacterial loads, increased
lung inflammation, and accelerated mortality compared to
mice with normal Smurf1 activity, Dr. Shiloh said.
Mice infected with a resistant strain of tuberculosis that were treated with both SMARt - 420 and ethionamide also showed a significantly reduced bacterial load in their
lungs three weeks after infection compared to controls, the authors report.
the team broke the virus down and inserted genes from the killer strain, one at a time, into a related but benign bird influenza virus that normally
infects only the
lungs of
mice.
Similar observations were noted at the Health Protection Agency (HPA) in the UK, where different morphotypes were observed from
lung samples in
mice infected with Bps K96243.
The
mice in both groups were then
infected with liver,
lung, or skin cancer through various methods.