Sentences with phrase «infected with our antibody»

«The cells that had been infected with our antibody library still showed marginal to undetectable differences from the control cells,» he said.

Perhaps he's an unpatched Windows system: if his pseudopod is still deep in my guts, I can infect it with an antibody.

Not exact matches

mothers who are infected with hepatitis C virus (persons with hepatitis C virus antibody or hepatitis C virus - RNA - positive blood)

At that time scientists knew that antibodies from people infected by the 1968 pandemic virus also reacted with an influenza strain isolated in 1963 from flu - ridden ducks.

And when the team injected antibody - treated cells into mouse brains, the animals showed no symptoms at all, whereas animals injected with prion - infected, but untreated, cells died after about 160 days.

Then they injected a new set of mice with strep antibodies from the infected mice.

«This study provides support for this idea that antibodies under certain conditions can be bad and actually cause severe disease when people are infected with dengue,» says viral immunologist Sujan Shresta of the La Jolla Institute for Allergy and Immunology in California.

When the team fed small groups of mice gliadin — a component of gluten — they found that mice produced two to three times as many antibodies against the compound over the next two days if they were also infected with reovirus.

In people infected with HIV who develop broadly neutralizing antibodies, this antibody region — called HCDR3 — has about 30 amino acids, about twice as long as what is usual for human antibodies.

Ethical concerns After two infected Americans were treated with a cocktail of antibodies made by Mapp Biopharmaceutical of San Diego, California, three UK - based international health experts called on 5 August for such drugs to be made available to Africans.

A small number of people infected with HIV produce antibodies with an amazing effect: Not only are the antibodies directed against the own virus strain, but also against different sub-types of HIV that circulate worldwide.

Antibodies derived from a type of immune cell found in unusually high numbers in HIV - infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV, scientisAntibodies derived from a type of immune cell found in unusually high numbers in HIV - infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV, scientisantibodies derived from a different type of immune cell more common in people without HIV, scientists report.

We know from HIV research that around one percent of people infected with HIV form antibodies that combat different virus strains.

The findings help explain why people infected with HIV can not sufficiently clear the virus with effective antibodies.

They examined around 4,500 people infected with HIV who are recorded in the Swiss HIV Cohort Study and the Zurich Primary HIV Infection Study, and identified 239 people who form such antibodies.

Notably, Crotty showed that the frequency of the Tfh cells correlated with development of broadly neutralizing antibodies against HIV in a large group of HIV - infected individuals.

It turned out that half the volunteers had antibodies to adenovirus 5, and one had previously been infected with the much rarer adenovirus 11.

They treated HIV - infected mice with antibodies that blocked type I interferons, which allowed the mice's immune systems to revert from the state of exhaustion.

-- Hyperimmune globulin, prepared by purifying and concentrating plasma of immunized animals or previously infected humans with high titers (concentrations) of neutralizing antibody against Ebola virus, which have been shown to be protective in monkeys but are not currently available and would not be expected before mid-2015.

For the study, Dr. Dadachova's team paired the monoclonal antibody (mAb2556) designed to target a protein expressed on the surface of HIV - infected cells with the radionuclide Bismuth - 213.

Interestingly, the anti-GalC antibodies were also found in patients without GBS who had recently been infected with mycoplasma.

Scientists are now asking whether the antibodies she makes to these proteins might protect her, at least in part, if her partner then becomes infected with HIV and exposes her to it.

Any mouse cells infected with the virus would produce both viral proteins and egg proteins, thus arousing antibodies that would attack proteins on the mouse eggs.

Memory cells recognize pathogens that have previously infected the body and quickly respond with the correct antibodies.

Follow - up studies showed that the two antibodies isolated from the Ebola patient work by interfering with a critical step in the process by which ebolaviruses infect cells and then multiply inside them.

Further searching turned up retroviral particles, which could kill white blood cells and which also reacted with antibodies from infected patients.

If such «antibody - dependent enhancement» (ADE) also takes place in people, it could have helped fuel Zika's recent explosion in Brazil, where more than 90 % of people in some communities have been infected with dengue.

They also saw that antibodies known to exhibit some effectiveness acted to prevent gp120 from opening, and that these effects correlated with a decrease in the virus» ability to infect cells.

But most of the recent patients were infected with Bordetella strains that have mutations in the genes for two key proteins thought to trigger production of immunizing antibodies.

Researchers assumed that African rodents must have their own menagerie of hantaviruses and that these might infect humans as well — an idea supported by studies that showed that some Africans carry antibodies that cross-react with Eurasian hantaviruses.

If infected with the dengue virus, the blood will contain specific antibodies produced by the body to attack the intruder.

Despite testing negative by antibody tests for Lyme disease, two of 10 subjects were still infected with Lyme bacteria in heart and bladder.

If, after a set reaction time, antibodies are found on the platform, the doctor will assume that the patient has been infected with the dengue virus.

Some people infected with HIV generate antibodies that fend off the virus successfully for decades.

Beyond this, the scientists also recommend combining of mo - lecular with serological tests which determine infection by detecting the antibodies developed by an infected person a few days after the infection.

Finally, Kurtis and colleagues used the antibody to develop a vaccine candidate that they gave to mice infected with a particularly lethal form of malaria.

(My admittedly wild hypothesis is that the gene, CD32, may help drive Zika virus to copy itself to higher levels if a person was previously infected with dengue and has antibodies to that virus.)

A vaccine such as this in the real world would work like a time bomb — a mosquito would pick up the antibodies only after infecting an individual with malaria.

Next, the team tested three of the antibodies in mice that had been infected with lethal doses of avian flu.

The technique involves injecting antibodies into tissue infected with the bacteria together with molecules called photosensitisers, which are harmless until they are activated by light.

Instead, they examined the patients» blood for antibodies and compared them with those found in the infected monkeys.

«This is a very promising first step for an HIV treatment approach using broadly neutralizing antibodies, and the first good news for some time for people infected with HIV,» says Pandey.

Several of the antibodies we isolated have broad neutralization capacity in vitro against divergent influenza strains and show potent prophylactic and therapeutic activity when used to treat mice that were lethally infected with influenza.

(B, C) Flow cytometric analysis of HIV - 1 gene expression in (B) mock infected or (C) latently infected CD4 + T cells under non-polarizing conditions, either at the basal state or after reactivation with antibodies against CD3 and CD28.

«A small fraction of people living with HIV can naturally produce exceptionally powerful and broad antibodies that could prevent HIV from infecting their immune cells, but not until several years post-infection — long after that protection can help them.

Julie Overbaugh, from the Fred Hutchinson Cancer Research Center in Seattle, USA, and colleagues characterized the antibodies generated in 21 women who were superinfected, that is, infected sequentially at least twice with HIV by different sexual partners.

The decreased levels of neutralizing Abs to TMAdV in the researcher (1 ∶ 32) and a family member (1 ∶ 8) relative to those in infected titi monkeys (up to > 1 ∶ 512) are consistent with a recent study showing much higher levels of neutralizing antibodies in chimpanzees than in humans with adenovirus infections, possibly due to more robust adenovirus - specific T - cell responses in humans than in monkeys [45].

HIV - 1 subtype E infected patients with broadened, dual (B / E) V3 loop serology have increased cross-neutralizing antibodies, AIDS Res and Hum Retroviruses, 17:69 - 79, 2001.

A new research study from University of North Carolina researchers shows that individuals who have been previously infected with a flavivirus — specifically dengue and Zika viruses — could have antibodies that protect against Zika.

Although most people infected with HIV produce antibodies against the virus within several weeks following infection, these antibodies rarely prevent the infection from progressing to full - blown AIDS.