After 381 days, this cow's antibodies prevented 96 percent of the 117 HIV types from
infecting cells in a lab dish.
Not exact matches
Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to
labs for use
in experiments, helped clear HSV - 1 infection
in cultured human corneal
cells,
in donated human corneas, and
in the corneas of mice
infected with HSV - 1.
The researchers found that the protein, called VRC07 - αCD3, triggered the activation and killing of latently HIV -
infected helper T
cells when the
cells were taken from patients on antiretroviral therapy and then incubated
in the
lab with the patients» own killer T
cells.
At the Galveston National Laboratory, which houses a biosafety level 4
lab, researchers shut down experiments, euthanized
infected animals, put pathogens
in cold storage, and autoclaved
cell cultures.
In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
In collaboration with Ding, the
lab of Olivier Voinnet at the Swiss Federal Institute of Technology
in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in Zurich also reported
in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in an accompanying paper the detection of viral siRNAs
in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in cultured mouse embryonic stem
cells infected by the Encephalomyocarditis virus.
The implications were hardly lost on the Bethesda crowd: If the virus was transmitted
in cell cultures
in Ruscetti's
lab, it could also be contaminating the nation's blood supply as a result of blood donations from unknowingly
infected donors.
When Liesman
infected human airway
cells in the
lab with this re-engineered virus, she saw
infected cells ball up and puff out of the airway epithelium.
In this lung organoid grown in Hans Clevers's lab, cells colored green are infected with respiratory syncytial viru
In this lung organoid grown
in Hans Clevers's lab, cells colored green are infected with respiratory syncytial viru
in Hans Clevers's
lab,
cells colored green are
infected with respiratory syncytial virus.
But even if XMRV is not a threat to human health, the fact that a retrovirus that can readily
infect human
cells was apparently generated by chance
in the
lab raises some interesting and potentially troubling issues.
The approach enabled a wide range of studies of human brain development, including implicating a new class of neural stem
cell recently discovered by the
lab in the evolutionary expansion of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly
in infants
infected in utero.
The findings — so far observed only
in cells and minibrains grown
in the
lab — offer a possible explanation for the misshapen heads that are the hallmark of microcephaly, a condition that afflicts some babies
infected with Zika.
In July labs at the University of California at San Francisco, University of Massachusetts Medical School, and MIT reported that they had used RNA - interference to arrest viral replication in cells infected with HIV and poli
In July
labs at the University of California at San Francisco, University of Massachusetts Medical School, and MIT reported that they had used RNA - interference to arrest viral replication
in cells infected with HIV and poli
in cells infected with HIV and polio.
Johannes Scheid, a student
in Nussenzweig's
lab, isolated it several years ago from an HIV -
infected patient whose immune system had an exceptional ability to neutralize HIV
in the blood by preventing the virus from
infecting and destroying a specific type of immune
cells, called CD4
cells,
in patients.
«This shows that the antibody not only can exert pressure on the virus, but also can shorten the survival of
infected cells,» says first author Ching - Lan Lu, a visiting student
in Dr. Nussenzweig's
lab.
Studying a new type of pinhead - size,
lab - grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way
in which Zika virus causes microcephaly and other damage
in fetal brains: by
infecting specialized stem
cells that build its outer layer, the cortex.
«To solve this problem, we borrowed a tool from phages themselves: the enzymes these viruses use to break apart a phage -
infected cell to release their progeny,» says Douglas Deutsch, a graduate student
in the
lab.
Five days post-stimulation the anti-CD3 / anti-CD28 coated magnetic beads were removed from each of the three cultures (non-transduced (NTD), AdX4 - ZFNs, and AdR5 - ZFNs) and 2.5 million
cells were seeded
in each of four cultures that were subsequently
infected with either Bk132 (primary X4 isolate), HxB2 (
lab - adapted X4 isolate), R3A (R5X4 primary isolate), or media only (mock).
Recently, Dr. Greene's
lab identified human protein fragments
in semen that enhance the ability of HIV to
infect new
cells — a discovery that one day could help stem the global spread of this deadly pathogen.
«We systematically screened over 50 methyltransferases to determine which ones regulate latency
in infected T
cells,» said Daniela Boehm, postdoctoral scholar
in the Ott
lab and first author of the study.