Sentences with phrase «infecting human cell cultures»

The research showed the beta - lactamase genes in Klebsiella pneumoniae were on all the time, whether or not the bacteria were infecting human cell cultures.

Not exact matches

But when the researchers added higher concentrations of BX795 to cultured human corneal cells infected with HSV - 1, the infection was quickly cleared.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).

Confocal microscopy of human neural stem cell culture infected with Zika virus (red).

The mutated, drug resistant H7N9 virus, however, was still able to infect cultured human cells and spread between laboratory animals as efficiently as nonmutated strains, researchers report December 10 in Nature Communications.

Greber and his team infected human cells in culture with the chemically labeled viruses, and observed the behavior of the viral DNA during entry into cells.

They found that indeed, they do, and that stimulating these cells led them to kill cells infected with HIV - 1 derived from latently infected cells, both in culture and in mice engineered to have a human immune system.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

But while researchers have previously been able to infect cultures of human hepatocytes with HBV, the cells» limited lifespan has made it difficult to study the virus, says Bhatia, who is also a Howard Hughes Medical Institute investigator and a member of MIT's Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

The new study, led by Walter Mothes, a Yale microbial pathogens expert, involved creating one culture that mixed healthy rat cells with cells infected by the murine leukemia virus, a cancerous pathogen in rats and monkeys that is not known to affect humans.

This protein can protect cultured human cells from avian influenza viruses but is ineffective against strains that have acquired the ability to infect humans.

Evidence of infection and replication of the two principal viral groups that infect humans was demonstrated for multiple passages of viruses through cell culture (Figure 1).

Our study shows that selecting the appropriate cell line, growing the cells as 3 - D aggregates and infecting them when they are fully differentiated is key for successful in vitro cell culturing of human noroviruses.»

CRISPR / Cas9 was able to eliminate HIV in infected human T cells in culture.

A study from Dr. Dusty Miller's laboratory indicates that Jaagsiekte sheep retrovirus (JSRV) infects both sheep and human cells cultured outside the body and does so by attaching to a receptor on the surface of lung cells.

Five years ago, the group reported that when they infected human tonsil cells with HIV in culture, 95 percent of the CD4 + T cells that died did so before the virus had a chance to reproduce within them.

Cells with similar characteristics accumulate during normal aging as well as in younger persons infected with human immunodeficiency virus, suggesting that the process of replicative senescence is not an artifact of cell culture but is also occurring in vivo.