Analysis of the tumour showed that it also been
infiltrated by macrophages.
Not exact matches
NF - kB enables cancer cells to survive the pro-apoptotic influence of tumor necrosis factor that is released
by tumor
infiltrating macrophages;
An early - stage clinical study
by another institution, published in the Lancet Oncology in May 2016, combined chemotherapy with an experimental drug that blocks CCR2, a receptor on monocytes and
macrophages whose activation stimulates these cells to
infiltrate tumors.
They first showed that mice with severed sensory nerves produce excessive BH4, churned out both
by the injured nerve cells themselves and
by macrophages — immune cells that
infiltrate damaged nerves and inflamed tissue.
However, muscle from both lean and obese animals was
infiltrated and surrounded
by adipose tissue that contained significant numbers of F4 / 80 - positive
macrophages (a and b).
These tumors were characterized
by the presence of
macrophages infiltrating the affected organs.