With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor
infiltration by immune cells).
Not exact matches
However, tumor
cells can circumvent this
immune defense
by establishing a surrounding microenvironment that prevents the
infiltration of NK
cells and thus promotes tumor survival and growth.
Cortisone helps to enhance the barrier function of the endothelium, preventing vascular leakage and further
infiltration of the alveolar space
by immune cells.
PEGylated arginine deiminase can modulate tumor
immune microenvironment
by affecting
immune checkpoint expression, decreasing regulatory T
cell accumulation and inducing tumor T
cell infiltration.
Here we present a novel human Airway Lung - Chip containing a fully - differentiated human mucociliary airway epithelium separated from a pulmonary microvascular endothelium
by a semi-permeable membrane that allows for
immune cell infiltration.
The underlying pathology involves
infiltration of the bowel wall
by inflammatory
cells due to altered
immune system function.
Lymphocytic thyroiditis, probably
immune - mediated, is characterized histologically
by a diffuse
infiltration of the gland
by lymphocytes, plasma
cells, and macrophages and results in progressive destruction of follicles and secondary fibrosis.