Sentences with phrase «infiltration of adipocytes»
Obesity is accompanied by ectopic lipid deposition in multiple tissues, including the skeleton, where infiltration of adipocytes into the bone marrow niche may negatively impact bone formation (7, 8).
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91 Normal functioning of adipose tissue is often (but not exclusively) impaired in obesity 91 and can be characterized by excessive hypertrophic adipocyte growth, elevated macrophage infiltration, hypoxia and dysregulated lipid storage.92