Sentences with phrase «inflammation in»

«If part of this is related to obesity, moderate exercise and reducing body weight can reduce chronic inflammation in the brain,» he said.
Arthritis is a chronic illness that sinks its claws into your body, and causes inflammation in your joints.
In people with IBD, inflammation in the digestive tract results in symptoms such as diarrhea and bleeding and can sometimes lead to intestinal obstructions or other severe complications.
Multiple sclerosis is characterized by an abnormal immune response that leads to inflammation in the brain and the destruction of myelin — a fatty sheath that protects and insulates nerve fibers.
«These findings question a long - held paradigm that myelin - specific T cells initiate inflammation in the brain through activation of microglia and brain macrophages,» says Scott Zamvil, MD, PhD, a professor of neurology at the University of California, San Francisco and co-author on the paper.
It comes down to proteins: specifically, a protein in the body that drives inflammation in the disease, the research found.
The University of Twente and Ziekenhuis Groep Twente researchers responsible for the development of the compact device believe that it may in time help doctors to objectively diagnose the degree of inflammation in joints.
Moreover, the new study indicates that this particular CLA fights inflammation in several ways at once.
Although c9, t11 also showed some weak anti-inflammatory action in the team's test - tube studies, it failed to curb inflammation in animals.
Obesity leads to a state of chronic, low - grade inflammation in liver and fat tissue, which in turn increases the levels of a pair of kinases: IKK - ε and TBK1.
The two main types, Crohn's disease and ulcerative colitis, develop from uncontrolled inflammation in the intestine, which can lead to severe diarrhea, pain, fatigue, weight loss and even death.
«With information about delirium risk, doctors can take steps before, during, and after surgery to reduce that risk,» for example, by reducing inflammation in patients with higher levels of CRP.
The researchers examined the role of inflammation in the nervous systems of Bb - infected animals.
These fatty acids may normally help dampen inflammation in the brain and protect neurons from damage, and lower levels in the brain have been implicated in several mental illnesses.
In the published paper, the team found that a protein known as Angiopoietin - like 4 (ANGPTL4) reduces inflammation in the early phase of wound healing in mice models.
In addition, people with more body fat may have higher blood levels of substances that cause inflammation in the joints, raising the risk for osteoarthritis.
For example, antibodies targeting amyloid - β peptide (Aβ) produce inflammation in the brain in some patients.
The adults had profound inflammation in the brain and movement disorders.
Hip and knee injections frequently are prescribed to alleviate pain and inflammation in patients with osteoarthritis.
An appropriate amount of inflammation in the body is beneficial for defense against bacterial infection, but uncontrolled inflammation leads to inflammatory diseases.
A high intake of fiber can help lower cholesterol, blood pressure and inflammation in the body, improve blood vessel function and prevent people from becoming overweight and obese.
Infection with Bb led to many histopathologic findings in infected animals not treated with dexamethasone, such as leptomeningitis, vasculitis, focal inflammation in the brain and spinal cord, and necrotizing focal neurodegeneration and demyelination in the cervical spinal cord.
Another unexpected finding was that an omega - 6 fatty acid (linoleic acid), which is present in vegetable oils, lessened inflammation in the fish.
The findings, published in the online journal Scientific Reports, identify a novel mechanism that resveratrol, a compound found naturally in some plant foods such as grapes, uses to alleviate inflammation in airway disease.
The study can't explain the association, but Vetter said it could be related to increased inflammation in the body and social disruption.
The primary outcome was aortic inflammation, as measured by 18 - FDG - PET / CT scans — an imaging technique that reveals inflammation in the aorta.
«If you block inflammation in people who don't have high levels of inflammation, you can do them a disservice,» Miller says.
Dr. Vállez García and the team are now considering what to look at next, such as inflammation in the brain or changes in the structure of other functional regions.
Produced by the liver, it indicates inflammation in the body.
In AS, inflammation in the joints and ligaments causes pain and stiffness in the neck, back and buttocks.
Immune cells are tricked into believing that they are lacking oxygen, leading them to retreat from the site of the inflammation in order to save energy.
While it is rarely fatal, chikungunya can cause severe, chronic polyarthritis (inflammation in multiple joints) and / or polyarthralgia (pain in multiple joints).
Their data suggest that the modulation of inflammation in the brain by IVIg is a key event that leads to the reduction in amyloid deposition.
Past research by Olefsky and others has shown that obesity is characterized by low - grade inflammation in adipose or fat tissues and that this inflammatory state can become chronic and result in systemic insulin resistance and diabetes.
«Recently, we became aware that some of the inflammation in CRS with nasal polyps is generated by the nasal lining itself, when a particular protein pump (P - glycoprotein) is overexpressed and leads to the hyper - secretion of inflammatory cytokines,» said senior author Benjamin S. Bleier, M.D., a sinus surgeon at Mass..
Receiving an injection of a steroid and anesthetic is a common treatment for patients who are experiencing pain and inflammation in a joint, such as the hip, knee or shoulder.
They created inflammation in the temporomandibular joints of the mice, and then measured bite force exerted by the mice to assess jaw inflammation and pain, similar to how TMJD pain is gauged in human patients.
They believe that this further contributes to the severe lung inflammation in chronic TB.
A human enzyme that can degrade the chitin of insect exoskeletons also regulates allergic inflammation in asthma, reinforcing the similarities between immune responses to parasitic and allergic stimuli.
Intestinal biopsy samples showed mild levels of microscopic inflammation in some of the children with autism, as well as in some of the non-autistic children.
Although scientists hypothesize that increased inflammation in fat tissue contributes to metabolic problems such as insulin resistance, this study found that metabolic function could improve while markers of inflammation remain unchanged.
One hepcidin inhibitor, called lexaptepid pegol (lexaptepid), has demonstrated efficacy in treating anemia of inflammation in animal studies.
In order to evaluate lexaptepid's potential in humans, investigators induced a safe and temporary model of anemia of inflammation in 24 healthy male adults and randomized them to receive lexaptepid or placebo.
Del - 1, a protein that blocks inflammation in the gums, was also discovered to be expressed in the brain.
«We have demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs, resulted in increased fat accumulation and inflammation in the liver of the adult offspring, raising new concerns about the long - term metabolic complications in children born to women who take SSRI antidepressants during pregnancy,» says PhD student Nicole De Long, who presented this research on June 22nd at the joint meeting of the International Society of Endocrinology and The Endocrine Society.
The prospective controlled clinical study tracked biological markers of inflammation in 150 pregnant women who had PCOS and 150 pregnant women of about the same age and body mass index.
For these reasons, the scientists hypothesized that Del - 1 might prevent inflammation in the central nervous system just as it does in the gum tissue.
They also hope to better understand the role of inflammation in the ability to generate new neurons.
At first, when the genetically modified mice were put in a sterile, germ - free environment, they did not develop MS.. When exposed to a normal environment that would normally contain bacteria, the mice did develop MS - like disease and inflammation in their bowels, suggesting gut bacteria is a risk factor that triggers MS disease development.
Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital (MGH) Center for Immunology and Inflammatory Diseases (CIID) have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.
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