Choi EY, Chavakis E, Czabanka MA, Langer H, Fraemohs L, Economopoulou M, Kundu RK, Orlandi A, Zheng YY, Prieto DA, Ballantyne CM, Constant SL, Aird W, Papayannopoulou T, Gahmberg CG, Udey MC, Vajkoczy P, Quertermous T, Dimmeler S, Weber C, and Chavakis T. Del - 1, an endogenous leukocyte - endothelial adhesion inhibitor, limits
inflammatory cell recruitment.
Del - 1, an endogenous leukocyte — endothelial adhesion inhibitor, limits
inflammatory cell recruitment.
Not exact matches
The tumors»
recruitment of these
inflammatory cells thus enabled them to resist what would otherwise have been a deadly dose of radiation, so that their growth slowed only modestly compared to control mice that had received no radiation.
Current thinking regarding type III hypersensitivity is that immune
cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release
inflammatory factors called cytokines that activate the endothelial
cells lining adjacent blood vessels to promote the
recruitment of neutrophils.
Jessica Jang, the lead author of the research paper and a third - year UCR graduate student in microbiology, explained that resistin regulates the
recruitment of innate immune
cells called monocytes to the site of infection to produce
inflammatory cytokines (small proteins that are important in
cell signaling).
Left: mast
cells are activated by allergens reacting with IgE bound to IgE receptors on the mast
cell surface to trigger the release of histamine and other
inflammatory mediators that orchestrate an allergic response including
recruitment of
inflammatory cells.
(A) Cellular and molecular mechanisms of immune
cell recruitment and activation in
inflammatory and metabolic disease.
With recent patient studies emphasizing the importance of inflammation in atherosclerosis and restenosis, the mechanisms that govern the
recruitment of
inflammatory cells are being investigated.
One of the earliest events in the development of atherosclerosis is the
recruitment of
inflammatory white blood
cells from the blood to the arterial wall by vascular
cell adhesion molecules (42).