Sentences with phrase «inflammatory gut diseases»

Concentrated milk fats, a common ingredient of processed foods and confectionery, trigger blooms of otherwise rare gut bacteria in mice that may contribute to inflammatory gut diseases.

«Research suggests new way to treat inflammatory gut disease and prevent rejection of bone marrow transplants.»

Not exact matches

They contribute to gut and immune health, and have reported benefits in treating and managing digestive disorders such as inflammatory bowel disease.

Omega - 3 rich sardines have a remarkable ability to help defend against mood disorders like depression and anxiety, ADHD, arthritis, infertility, heart disease and inflammatory gut conditions like ulcerative colitis and Crohn's disease.

When our digestive junctions are loose, this can lead to compounds entering the bloodstream where they shouldn't be, which may contribute to leaky gut and other immune - activated conditions like inflammatory bowel disease.

Maybe you're reading this because you want to learn more about your gut and the way it influences your health or perhaps you're suffering from an autoimmune condition or digestive disorder, food allergy or intolerance, inflammatory bowel disease or inflammatory bowel syndrome, Coeliac disease, thyroid issue, diabetes, obesity, arthritis or fibromyalgia.

While nightshades are healthful for most people, according to Dr. Axe, people who struggle with food sensitivities, allergies, autoimmune disease, inflammatory bowel disease or leaky gut syndrome may find that they contribute to the condition.

Breastfeeding has many benefits that include protecting the baby against inflammatory diseases of the gut, lungs or ears, and longer term health problems such as diabetes and obesity, improved cognitive outcomes, and protecting the mother against breast cancer.

As part of the study, researchers found that mice engineered to develop symptoms of human inflammatory disease, and which also lacked the ATG16L1 gene, developed gut damage.

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

The study found that a mother mouse can pass along to her offspring a susceptibility to intestinal disorders, such as inflammatory bowel disease, by way of a gut - residing bacterium called Sutterella, the researchers reported in the journal Nature on Feb. 16.

If this applies to gut bacteria too, it could explain higher rates of allergies and other inflammatory diseases in rich nations.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.»

«How the microbiome is linked to autoimmune disorders: Discovery of new mechanism in the gut microbiome has implications for inflammatory bowel disease.»

The DNA - damaging bacterium is found to flourish in the guts of mice with inflammatory bowel disease, putting them at higher risk for colorectal cancer

Researchers uncovered the following pathway: gut bacteria stimulate intestinal B lymphocytes to release interleukin (IL)-10 that, in turn, induces development of regulatory T lymphocytes that prevent excessive inflammatory responses and limit immune - mediated disease.

As changes in gut flora could increase the risk of some chronic diseases, such as inflammatory bowel syndrome, each course of antibiotics may represent a trade - off between short - term benefit and long - term risk.

«Like zebrafish, we have this rich source of gut microbes that have figured out how to coexist with us and soothe the immune system,» she says, adding that «there is enormous potential to harness those mechanisms» to address ailments such as inflammatory bowel disease and other chronic inflammation.

Changes in the composition of the gut microbiota are seen in many human diseases such IBD, a chronic, lifelong inflammatory disorder that includes Crohn's disease and ulcerative colitis.

Dr Grainger and his team are now working with other groups at The University of Manchester to carry out further studies on monocytes, particularly from patients with inflammatory conditions, and are focused on identifying situations where this gut information system may have gone wrong such as in inflammatory bowel diseases.

Outside the gut, these bacteria prompt an inflammatory response that can lead to a cascade of other diseases.

Mutations in the human genome may cause shifts in the gut bacteria of patients with inflammatory bowel disease.

«Oral bacteria in the gut could drive immune cell induction and inflammatory bowel disease.»

Their findings suggest a profound association between oral microbe and gut ecosystem, which provides new insights into microbiome research, and advance development of a novel type of medicine in therapeutics of chronic inflammatory diseases.

«We noticed that oral microbes are relatively enriched in gut microbiomes of patients with several diseases such as inflammatory bowel disease (IBD), HIV infection, and colon cancer compared with healthy individuals.»

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the condition.

These studies demonstrate that inflammatory intestinal pathologies, such as Hirschsprung - associated enterocolitis or inflammatory bowel disease, can be explained as an overgrowth of certain pro-inflammatory groups of bacteria or a loss of anti-inflammatory bacteria, said Judith Eisen, a professor of biology and an expert on gut neurons in zebrafish.

«In the future, such efforts could allow us to much better understand human - microbiome interactions, model malnutrition disorders and inflammatory diseases of the gut, and perform personalized drug testing,» said co-first author Alessio Tovaglieri, a Graduate Student at the Department of Health Science and Technology at ETH Zurich in Switzerland, who performs his thesis work on Ingber's team.

«This new class of immunotherapy drug traps white blood cells in the lymph nodes to prevent their escape into the gut where they cause inflammation,» said William J. Sandborn, MD, professor of medicine at UC San Diego School of Medicine and director of the Inflammatory Bowel Disease Center at UC San Diego Health.

Inflammatory bowel disease (IBD), characterized by chronic relapsing inflammation of the gut, is a common problem in the industrialized world.

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease (IBD).

Chassaing and Gewirtz hypothesized that emulsifiers might affect the gut microbiota to promote these inflammatory diseases and designed experiments in mice to test this possibility.

There is an intimate link between uncontrolled inflammation in the gut associated with inflammatory bowel disease and the eventual development of colon cancer.

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

«An association between a history of chronic diarrhea and the risk of developing RA supports the hypothesis of dysbiosis (a bacterial imbalance in the gut) as a risk factor for the emergence of immune - mediated inflammatory disease,» explained Professor Seror.

«Obesity, metabolic syndrome, inflammatory bowel syndrome, and liver disease have already been linked with changes in bacterial composition of the gut.»

Research Interests: Inflammatory bowel disease (IBD); Crohn's disease; ulcerative colitis; animal models of IBD; mucosal T - cell death and survival; tolerance to gut microbiota; interactions between immune and non-immune cells; immune - driven angiogenesis and lymphangiogenesis; intestinal fibrosis; intestinal myofibroblasts, extracellular matrix; systems biology; complex diseases

Through its IBD and Crohn's Disease Program, the Helmsley Charitable Trust supports the Crohn's & Colitis Foundation of America (CCFA) to better understand how microorganisms in the gut contribute to this recurring inflammatory condition.

The role of inflammation in temporal shifts in the inflammatory bowel disease mucosal microbiome — Christopher John Kiely — Gut Microbes

July 21, 2016 Antibiotic treatment weakens progression of Alzheimer's disease through changes in the gut microbiome Long - term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.

«Omics Tech, Gut - on - a-Chip, and Bacterial Engineering» featured three new approaches to studying a suite of gastrointestinal illnesses called inflammatory bowel diseases (IBDs), which impact at least 1 million Americans and many more worldwide.

«We see this atlas providing a foundation for investigating many different questions about the pathology in the gut, effects of drug - induced gut toxicities and for identifying and examining important cells, interactions, and biomarkers,» said Xavier, who is also chief of gastroenterology and director of the Center for the Study of Inflammatory Bowel Disease at MGH.

This census, published in Nature, comprises a first - draft atlas of the small intestine's cellular composition, providing a reference for studying the biology of a host of conditions affecting or involving the gut, such as inflammatory bowel disease, cancers of the small intestine, celiac disease, and food allergies.

There are strong associations between the human gut microbiome and conditions including obesity, type - 2 diabetes, cirrhosis, rheumatoid arthritis and inflammatory bowel disease.

In the gut, malfunction of autophagy has been related to inflammatory bowel disease (IBD) and cancer progression.

Inflammatory bowel disease represents a complex interaction between genetics, gut bacteria, the body's immune system, and the environment.

Background: Inflammatory bowel diseases (IBD) are believed to be driven by dysregulated interactions between the host and the gut microbiota.

For example, lower diversity of the gut microbiome has been associated with obesity and inflammatory bowel disease (IBD), and higher diversity in the vagina with bacterial vaginosis.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host — Gut Microbiota Interactions during Inflammatory Bowel Disease — Andrew Leber — Frontiers in Immunology