Sentences with phrase «inflammatory microenvironment»

«Hypoxia can occur for many reasons, but in early FOP flare - ups, we speculated that hypoxia might result from the inflammatory microenvironment in lesions,» Kaplan said.

But mounting evidence implicates the immune system in the overproduction of cell - signalling molecules called cytokines, which stimulate skin cells called keratinocytes to express genes that maintain an inflammatory microenvironment.

Not exact matches

It is believed that chronic wounds get stuck in an inflammatory phase, with a low - oxygen microenvironment and the persistent presence of enzymes that break down tissue proteins.

A specific genetic mutation in these cells results in inflammatory injury to the microenvironment and this control breaks down.

the role of the microenvironment created by inflammation and the inflammatory signaling molecules in the formation and progression of tumors

Similar to a pathogenic response to an invading bacterium, excess nutrients found in the obese adipose microenvironment can lead to the pro-inflammatory activation and phenotypic switch (from M2 resident to M1 inflammatory macrophage) of macrophage [24].