Huntington's monkeys also show levels of inflammatory markers (cytokines and
inflammatory pathway genes) in their blood that is greater than in controls.
Not exact matches
Many of the
genes identified by Dr. Papapanou and his team are implicated in immune and
inflammatory pathways, confirming laboratory and clinical observations of the development of periodontal disease.
On the flip side, turning up expression of these
genes or their
pathways could help researchers grow new intestinal tissue to replace tissue destroyed by diseases such as
inflammatory bowel disease or radiation treatment for cancer.
«Without zinc present in sufficient quantities, the JAK - STAT
pathway keeps giving the
genes the «on» signal, and continues production of this
inflammatory protein,» said Knoell.
Pathway analysis also found changes in
genes linked to the immune system, the body's
inflammatory response, and cells» energy metabolism.
Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the binding of NF - kB to DNA by blocking the transcription of different
genes involved in both
inflammatory and aging
pathways (interlukin - 6, interlukin - 1 beta, tumor necrosis factor alpha) 27.
The team ran
gene - expression arrays to shed light on the genetic
pathways at play, focusing on interferon gamma, a signaling molecule involved in the
inflammatory response.
His research focuses on understanding the role of inflammation in retinal degenerative diseases and seeks to target
inflammatory pathways in these diseases using
gene therapy.
The incredible ability of curcumin to promote various
pathways like
gene transcription factors,
inflammatory cytokine
pathways and various growth factors means that it has been studied for the many potential benefits for skin conditions like psoriasis, skin cancers, dermatitis, acne, wound healing and even keloid scars.