Sentences with phrase «influence epigenetic modifications»

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Epigenetic changes, the chemical modifications of DNA that are the result of environmental influences, are the results of long term events lasting months or years, like famines.

A new study suggests that epigenetic effects — chemical modifications of the human genome that alter gene activity without changing the DNA sequence — may sometimes influence sexual orientation.

These so - called epigenetic modifications can influence a variety of traits, such as obesity and sexual preference.

Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain

Epigenetic modifications are partly inherited, but unlike the genome itself, are cell specific, plastic, and responsive to environmental influences.

The majority of that specialization is governed by epigenetic changes — histone modifications, DNA accessibility, and methylation — that influence when and how genes are expressed.

The molecules central to this balancing act, H3K4me3 and H3K27me3, are among the so - called epigenetic modifications that influence the activity patterns of genes in both human embryonic stem (ES) cells and mature human adult cells.

We have previously shown that epigenetic modifications may accumulate during aging (5,6), and that DNA methylation in humans is influenced by diet, birth weight, and exercise (7 — 10), suggesting that epigenetics could be involved in age - related and life style — related diseases such as T2D.

Since the methylation of cytosine does not alter the DNA sequence, but only influences when and where these proteins are produced, it is considered an epigenetic modification.

Epigenetic modifications of promoter regions that influence the transcription of genes coding for crucial protein products can be induced by the environment.

Fathers may have heritable physiological impacts on their children via genetic and epigenetic mechanisms that begin to emerge shortly after conception12 and which may influence maternal investment during pregnancy.13 Older fathers tend to transmit more mutations to their offspring, 14 while early childhood paternal stressors predict children's adolescent gene methylation patterns (a type of chemical modification of DNA).15