Sentences with phrase «influence on cancer»

The relative contribution of intrinsic (e.g. genetic) and extrinsic (e.g. environmental) risk factors in cancer development is the subject of a paper published in the journal Nature, which reports that external risk factors have a greater influence on cancer risk compared to intrinsic risk factors which only contribute modestly.

Genetic testing also can reveal many that have unknown consequences for the function of these genes, so their influence on cancer risk can't be predicted.

Both of these excellent researchers have been driving progress in the crucial area of nutritional influences on cancer proliferation.

Not exact matches

Before her cancer diagnosis Chiara Luce Badone had been influenced by the Focolare movement and its focus on Jesus» cry on the cross, «My God, my God why have you forsaken me», as the moment in which he reunites us to God and to each other.

An earlier study that didn't take parental influence into account found one variant on chromosome 11 raised the risk of breast cancer by 7 per cent.

It has been suggested that localization of colon cancer on either the right or left side may influence prognosis because of differing biological features.

Kornelia Polyak, an oncologist at Harvard Medical School in Boston, says that cancer researchers tend to focus on the mutations inside cells, and fail to consider how those mutated cells might influence the cells around them.

«While the presence of lymphocytes in tumors is often associated with better clinical outcomes, this research adds clarity on the diversity of T cells within the tumor environment and their influence on ovarian cancer outcomes,» says first author Kunle Odunsi, MD, PhD, FRCOG, FACOG, Deputy Director, M. Steven Piver Professor and Chair of Gynecologic Oncology, and Executive Director of the Center for Immunotherapy at Roswell Park.

«This study also adds greater understanding of tumor - infiltrating lymphocytes and their influence on the causes and progression of ovarian cancer.

«Although the effects of the drug were modest, we now know that we can influence the course of the disease, and we expect to build on this success with other drugs, including some already in development,» said senior author, Gary K. Schwartz, MD, professor of medicine and chief of hematology / oncology at NewYork - Presbyterian / Columbia University Medical Center and associate director of its Herbert Irving Comprehensive Cancer Center.

Researchers using data collected by the Ovarian Cancer Association Consortium have discovered uncommon variants in new regions of the genome that influence ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San DiegCancer Association Consortium have discovered uncommon variants in new regions of the genome that influence ovarian cancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San Diegcancer risk, and will present their findings on April 6, 2014 at the American Association for Cancer Research Annual Meeting in San DiegCancer Research Annual Meeting in San Diego, CA.

The influence of medication on cancer diagnosis was also studied.

These are some of the insights drawn from research by Michelle Sowden and colleagues of the University of Vermont in the US to determine if living in a rural or urban area influences the impact of cancer diagnosis on employment.

Researchers developed models to examine the influence of driver mutations — mutations that promote cancer development — on the initiation and development of gliomas, and how tumor genomic profiles evolve as the cancer progresses.

«How the virus infects and replicates has a direct influence on how the cell becomes a cancer cell,» Gao said, adding that you can not cure cancer without some kind of roadmap.

If, as some people believe, the mind can have a positive influence on the immune system — which in turn can fight off cancer — it would stand to reason that R., who was terribly stressed, might have been expected to do very badly.

Beyond offering further proof that single genes can have dramatic influences on longevity, an idea that drew skepticism just a decade ago, the new finding may help scientists explain how severely reducing calorie intake extends life span in a variety of animals (SN: 11/25/00, p. 341: Low - cal diet may reduce cancer in monkeys).

Since diet can influence insulin activation, the researchers wondered whether diet could impact breast cancer prognosis based on expression of the IGF1 receptor in the primary breast tumor tissue.

«GECCO aims to continue to discover additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle risk factors, including biomarkers as well as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer risk.

Her dissertation looked at whether variants in the PSA gene — that is, the gene that codes for the PSA (prostate specific antigen) protein doctors use as a screen for the existence or recurrence of prostate cancer — had any influence on developing the cancer.

To illustrate potential mutation - specific effects on absolute cancer risks, we used the hazard ratio estimates to derive approximate absolute risks and 95 % confidence intervals, based on published estimates for the overall risks of breast and ovarian cancer by age 70 years.26 These estimates are for illustration and do not represent absolute risk estimates that would be required in a genetic counseling setting, as they do not account for noncancer outcomes that may influence a woman's life expectancy, the effects of family history, and nonrandom ascertainment of mutation carriers in this sample and depend on assumptions about the prevalence of different mutation classes in the population.

Additionally, I work on the Th2 cytokines IL4 and IL13 and their receptors, and how these molecules can influence malignant progression of breast and colon cancers.

She is widely recognized for her work on senescent cells — older cells that have stopped dividing — and their influence on aging and cancer.

It's possible that inherited regions of CNV with strong influence on gene expression are targeted for amplification / deletion by cancer cells, which might obscure their effect in an otherwise normal cell.

With a team of over 200 researchers, Sanford Research is comprised of eight groups that bridge bench, translational and clinical research including: Cancer Biology and Immunotherapies, Pediatrics and Rare Diseases, Diabetes, Cellular Therapies and Stem Cell Biology, Enabling Technology, Environmental Influences on Health and Disease, Genetics and Genomics, and Population Health.

Regardless of how immunotherapy could eventually influence cancer treatment, its development is a new revolution in cancer treatment, building on detailed biochemical knowledge of how cancer mutates and evades the immune response.

Research Director, Silent Spring Institute Website Ruthann Rudel is the research director at Silent Spring Institute, where she leads major exposure and toxicology research programs focusing on hormonally active chemicals and biological mechanisms by which chemicals may influence breast cancer.

Influence of gemcitabine chemotherapy on the microbiota of pancreatic cancer xenografted mice.

Influence of mindfulness - based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC).

According to recent research, the most common solid tumors (that is, cancer that occurs as clusters of cells in or on organs, rather than in liquid form within the blood or lymphatic system) have up to 66 mutations that influence how the cancer cells operate — how fast they divide, whether they are susceptible to the signals that would normally cause a cell to die, when they detach from the main tumor to colonize another organ in the body, when and where they attach blood vessels to healthy tissues.

Cancer can also occur when certain normal genes (tumor suppressor genes, for example) are «switched on or off» as a result of environmental epigenetics — influences that occur throughout your life.

While much of the focus has been on the maternal side, few if any studies have looked at the influence of dad's overweight and obesity on his offspring's cancer risk.

An international team led by researchers at the Broad Institute of MIT and Harvard, the Harvard T.H. Chan School of Public Health and Fred Hutchinson Cancer Research Center uncovered the influence of genetic variation on vaccine effectiveness after applying cutting - edge DNA sequencing technology to almost 5,000 patient blood samples.

GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3d).

This dichotomy points out the importance of an indirect influence on proteins whose altered function is required during carcinogenesis but are too essential to be mutated (i.e., mutation of their encoding genes could decrease the viability of cancer cells).

Being overweight and alcohol consumption were found to have less influence on risk of breast cancer.

Mind - body medicine for cancer explores the influence of your mind, emotions, traumas on your body, immune system, and vice versa.

«Thus, replacement of meat protein with soyabean protein, as tofu, may have a minor effect on biologically - active sex hormones which could influence prostate cancer risk.»

Some cancers develop mutations that serve the purpose of increasing the influence of insulin on the cell; others take advantage of the elevated insulin levels that are common to metabolic syndrome, obesity and type 2 diabetes.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.

As if cancer wasn't challenging to begin with, secondary attacks on the immune system from environmental pathogenic influences, such as viruses and bacteria, make the immune system particularly vulnerable in those already experiencing oncological issues.

But, there are still many questions about what specific influences diet and exercise can have on cancer risk factors.

Also check out my related blog posts for more context: Eating To Extend Our Lifespan; Dietary Guideline Graphics: From the Food Pyramid to My Plate, Harvard's Healthy Eating Plate, and PCRM's Power Plate; Stool Size and Breast Cancer Risk; Avoiding Dairy to Prevent Parkinson's; Industry Influence on Dietary Guidelines; and Raspberries Reverse Precancerous Lesions.

According to an article posted on Sciencedaily.com on December 8th 2011, entitled «Starch Intake May Influence Risk for Breast Cancer Recurrence, Study Suggests», starch intake (Note: specifically starch, and not just any old carbohydrate) is responsible for an increased risk of breast cCancer Recurrence, Study Suggests», starch intake (Note: specifically starch, and not just any old carbohydrate) is responsible for an increased risk of breast cancercancer.

In fact, exactly how the gut microbiome «interacts with foods to produce health conditions» is considered a new and dynamic area for further research by individuals on all sides of the red meat - colon cancer debate.10 For example, researchers at Harvard Medical School are studying fecal samples to assess the impact of red meat intake on gut microbes and their byproducts, which the researchers speculate may influence «biological pathways associated with colorectal cancer and other digestive diseases.»

Eng's team decided to look at whether genes on the X chromosome passed down from the father might influence a daughter's risk of ovarian cancer.

I think the changes I will make will be to stop taking Flax supplementation (links to prostate cancer mentioned on Mark's Daily Apple also influence this) and to stop using tahini as a condiment.

Perhaps, as Giovannucci and colleagues (1992) suggest, intake of Dietary Fiber may influence the early stages of carcinogenesis, whereas dietary fat may have a greater influence on the progression of initiated cells into cancer.

A meta - analysis of 9 cohort and 9 case - control studies found a borderline significant influence of highest coffee consumption on the risk of breast cancer.

Your family history can influence your own risk, so get to the bottom of your family's cancer history on both your mother's and father's sides.