The study, co-led by Mats Nilsson (Stockholm University / SciLifeLab) provides new strategies for evaluating how new mutations affect pathogenicity and identifying properties that enable or restrict
influenza gene segment reassortment that give rise to to -LSB-...]
Influenza gene segments visualized in cells during replication.
The cell nuclei are in grey and
the influenza gene segments are labeled as dots with a particular color.
Not exact matches
By developing a new technique for labeling the
gene segments of
influenza viruses, researchers now know more about how
influenza viruses enter the cell and establish cell co-infections — a major contributing factor to potential pandemic development.
Our collaborative
influenza projects: 1) characterizing the temporal and spatial evolutionary dynamics of the IAV and IBV circulating globally in humans and wild birds, 2) identifying the IAV genotypes circulating in pigs at county fairs (swine - human interface) to determine if fairs produce novel reassortants or enable zoonosis / reverse zoonosis, 3) determining if specific internal
gene segment constellations enhance viral fitness, 4) detecting epistatic interactions between
gene segments, and 5) assessing the impact of inter-hemispheric migration of viruses /
gene segments.