Researchers found that a dominant mutation in CLPX
inherited by members of this family reduced the degradation associated with one of its target proteins, ALAS, which subsequently led to the accumulation of protoporphyrin IX (PPIX).
Not exact matches
Hereditary: Hereditary cancer is caused
by abnormal, or mutated, genes that are passed down through generations within a
family, causing
family members who
inherit the mutation to be diagnosed with certain types
of cancers.
Animals come to live in plural households
by (1) acquisition — e.g., a
family adopts a pet, a
member of the household
inherits Aunt Celia's African Gray, house partners take in the cat the neighbors abandoned, and so on; or (2) blending — people move in together bringing their respective companion animals to the mix.
Mibu Kamishiro (voiced
by Yuusuke Shirai): a
member of a distinguished
family, who is poised to
inherit the
family business (he's been working in management since a pretty young age).