Many other natural anti-angiogenic compounds
inhibit endothelial cell proliferation [9], [10], [24], [25].
Synthetic heparan sulfate oligosaccharides
inhibit endothelial cell functions essential for angiogenesis.
Not exact matches
Genentech scientists led by Mark Dennis designed an antibody with two arms — one that binds to BACE1 and
inhibits its activity and one that binds to the transferrin receptor and tricks
endothelial cells into transporting the antibody across the blood - brain barrier.
MicroRNA - 24
inhibits the proliferation and migration of
endothelial cells in patients with atherosclerosis by targeting importin - a3 and regulating inflammatory responses.
MicroRNA - 138
inhibits hypoxia - induced proliferation of
endothelial progenitor
cells via inhibition of HIF - 1a - mediated MAPK and AKT signaling.
Rhinocetin, a Venom - derived Integrin - specific Antagonist
Inhibits Collagen - induced Platelet and
Endothelial Cell Functions.
Egg - Derived Peptide IRW
Inhibits TNF - α - Induced Inflammatory Response and Oxidative Stress in
Endothelial Cells.
Anastellin, a fragment of the first type III repeat of fibronectin,
inhibits extracellular signal - regulated kinase and causes G1 arrest in human microvessel
endothelial cells.
Josin researchers made two major findings: They identified the mechanisms by which GLP - 1 can induce protective actions on the glomerular (renal)
endothelial cells by
inhibiting the signaling pathway of Ang II and its pro-inflammatory effect; and demonstrated a dual signaling mechanism by which hyperglycemia, via PKCβ activation, can increase Ang II action and
inhibit GLP - 1's protective effects by reducing the expression of GLP - 1 receptors in the glomerular
endothelial cells.
These measures include enhancing the flow of urine by achieving and maintaining proper hydration, promoting a pH that will
inhibit the growth of the organism, and preventing bacterial adherence to the
endothelial cells of the bladder.
Resveratrol has been found to
inhibit the expression of adhesion molecules in cultured
endothelial cells (43, 44).