Sentences with phrase «inhibit osteoclast»

Denosumab, a fully human monoclonal antibody drug, binds specifically to RANK - ligand (RANKL) and inhibits osteoclast - induced bone resorption by preventing the binding of RANKL to RANK.

Research has shown that strontium may play a role in the formation of osteoblasts, new bone forming cells, while at the same time slowing the breakdown of old bone by inhibiting osteoclasts.

Not exact matches

With this new understanding of how Del - 1 can inhibit periodontal bone loss — both by reducing inflammation and by restraining the activity of osteoclasts that resorb bone tissue — the researchers tested it, in a preclinical model of periodontitis observing that Del - 1 significantly reduced inflammation and tissue damage and that there was significantly less bone loss.

Initially, fluoxetine protects bone by inhibiting the cells in the skeleton (osteoclasts) that constantly break down and resorb bone.

Maran A, Gorny G, Oursler MJ, et al. 2 - methoxyestradiol inhibits differentiation and is cytotoxic to osteoclasts.

It stimulates the production of calcitonin, the hormone responsible for inhibiting cells (osteoclasts) that breaks bone down and activates alkaline phosphatase, an enzyme that forms new calcium crystals in bones.

And they found that blood serum obtained following the consumption of an almond meal inhibits human osteoclast formation, function, and gene expression, providing direct evidence to support the association between regular almond consumption and a reduced risk of developing osteoporosis.