Sentences with phrase «inhibit tumor cell growth»

Apple extracts also contain bioactive compounds that inhibit tumor cell growth in vitro.

The compound then was tested in an experimental model for melanoma and found to significantly inhibit tumor cell growth without appreciable toxicities.

Not exact matches

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

Mogroside V has been found in research to have the ability to inhibit tumor growth in pancreatic cancer by interfering with the rapid dividing of cancer cells, preventing angiogenesis (blood flow to the tumor), and even promoting cancer cell death (10).

Cancer: Flaxseed may protect against breast cancer, prostate cancer, and colon cancer by inhibiting tumor growth and blocking enzymes that are involved in the spread of tumor cells.

The substance vigorously inhibited the growth of cultured tumor cells from colon, lung, and breast cancers, the team reports in the 20 January issue of Angewandte Chemie.

Overexpression of ZMYND11 in an osteosarcoma cell line and a triple - negative breast cancer cell line inhibited tumor growth.

Terbinafine, a U.S. Food and Drug Administration — approved antifungal drug targeting SQLE, markedly inhibited SQLE - induced NAFLD - HCC cell growth in NAFLD - HCC and HCC cells and attenuated tumor development in xenograft models and in Sqle transgenic mice.

«We demonstrated that alpha - KGDH interacts with Gcn5 in the cell nucleus and found that tumor cell proliferation and tumor growth were inhibited when alpha - KGDH was blocked from entering the cell nucleus or by disruption of Gcn5's binding to succinyl - coenzyme A,» said Lu.

«Bringing natural killer cells to the tumor battlefield: Scientists discover a mechanism that inhibits tumor growth in skin cancer.»

Other studies have found that nutrients in dark, leafy greens may inhibit the growth of tumor cells in breast, skin, lung and stomach cancers and that green tea may thwart cancer development in colon, liver, breast and prostate cells.

Drugs like fluorouracil, oxaliplatin and irinotecan work by mimicking and damaging DNA molecules, or inhibiting enzymes involved in cell and DNA replication, slowing the uncontrolled growth of tumor cells.

Cranberries also contain a number of compounds that benefit human health — including some that have been shown to inhibit the growth of tumor cells — and sequencing work may reveal more about them.

One drug attacks cancer cells; the other inhibits cancer cell formation and the growth of blood vessels at tumor sites.

Since cancer cells bear very specific antigens on the surface, the corresponding antibodies bind to these molecules and thus inhibit tumor growth.

To test this, researchers inhibited the ability of Runx2 to be phosphorylated in cancer cells and found that tumor growth was reduced.

The two most widely used drugs to treat colorectal cancer act to either inhibit enzyme activity of cancer cells or arrest tumor cell growth.

She also noted the targeting Msi in primary tumors significantly changed «the trajectory of progression by halting pancreatic cancer growth and improving survival,» inhibiting both cancer stem cells and other tumor cells.

When a chemical that inhibits entosis was applied to a line of breast cancer cells, colony formation — an indicator of tumor growth in vitro — increased 10-fold.

All of these foods contain the inositol phosphate IP5 — a compound that even at low dose limits the supply of blood to tumor cells and inhibits tumor growth in mice, according to new findings.

In the study, the compound caused human melanoma cells to die and inhibited tumor growth by about 69 percent in a mouse model.

These compounds have been shown to inhibit cancer cell growth, induce cancer cell apoptosis, and reduce tumor volume in mice (14, 15, 16, 17).

Using animal models and cells, Counter and colleagues found that when they experimentally inhibited copper uptake by tumors with the BRAF mutation, they could curb tumor growth.

In a previous study, Lonard and co-senior study author Bert O'Malley of Baylor College of Medicine screened a large number of compounds to identify SRC - inhibiting molecules that kill a wide variety of cancer cells and inhibit tumor growth in animal models.

[i] Furthermore, [we] demonstrated that an MHC like molecule, called CD1d, loaded with a glycolipid ligand, called alphaGalCer, also targeted to the tumor cells by monoclonal antibodies, was capable to specifically inhibit tumor growth in vivo and to give a sustained activation of the Natural Killer Cells known to be important in the innate immucells by monoclonal antibodies, was capable to specifically inhibit tumor growth in vivo and to give a sustained activation of the Natural Killer Cells known to be important in the innate immuCells known to be important in the innate immunity.

Itraconazole Inhibits Angiogenesis and Tumor Growth in Non — Small Cell Lung Cancer.

Now, in Stem Cells Translation Medicine, the group of Shu Wang at the National University of Singapore describe the derivation of EPCs from human iPSCs, their therapeutic modification, and their ability to inhibit tumor growth in a mouse breast cancer model [4].

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth.

Immune cells initially inhibit tumor growth; however, tumor cells often suppress not only the tumor - inhibitory function of immune cells, but they can also hijack immune cells to promote tumor growth.

Downregulation of tumor suppressors and upregulation of proto - oncogenes can directly inhibit the ability of a cell to undergo programmed cell death while simultaneously stimulating growth and division.

8/7/2008 Researchers Discover How Tumor Suppressor Inhibits Cell Growth Genes that inhibit the spontaneous development of cancer are called tumor suppressor gTumor Suppressor Inhibits Cell Growth Genes that inhibit the spontaneous development of cancer are called tumor suppressor gtumor suppressor genes.

Evidence demonstrating its cytostatic activity includes the finding that it inhibits the growth of a broad spectrum of human tumor cell lines in vitro.

Sandoval F, Terme M, Nizard M, Badoual C, Bureau MF, Freyburger L, Clement O, Marcheteau E, Gey A, Fraisse G, Bouguin C, Merillon N, Dransart E, Tran T, Quintin - Colonna F, Autret G, Thiebaud M, Suleman F, Riffault S, Wu TC et al. (2013) Mucosal Imprinting of Vaccine - Induced CD8 + T Cells Is Crucial to Inhibit the Growth of Mucosal Tumors.

Tran T, De Oliveira Diniz M, Dransart E, Gey A, Merillon N, Lone YC, Godefroy S, Sibley C, Ferreira LC, Medioni J, Oudard S, Johannes * L, Tartour * E (2016) A therapeutic Her2 / neu vaccine targeting dendritic cells preferentially inhibits the growth of low Her2 / neu - expressing tumor in HLA - A2 transgenic mice.

We found that canonical signaling by the EphB4 receptor is low in breast cancer cells and that ephrin - induced stimulation of EphB4 kinase activity inhibits breast cancer cell malignancy in culture and tumor growth in vivo (Figure 1A) through inhibition of the CRK proto - oncogene.

Further studies showed that Notch1 knockdown in NSCLC helps induce cell death (which inhibits tumor initiation and growth); this process is mediated by p53, and thus the effects of inhibiting Notch1 require functional p53.

that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

Since 2012, two drugs that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

Flaxseed is also a great source of lignans, plant compounds that have been shown to inhibit the growth of colon tumor cells.

In laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animals.

Ricker JL, Chen Z, Yang XP, et al. 2 - methoxyestradiol inhibits hypoxia - inducible factor 1alpha, tumor growth, and angiogenesis and augments paclitaxel efficacy in head and neck squamous cell carcinoma.

They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.

Cancer cell growth and tumor growth seems to be inhibited by the compounds that medicinal mushrooms contain.

These good fats help regulate cell reproduction, inhibit tumor growth, boost the immune system and reduce inflammation.

As a result, breast cancer cell growth is blocked One study in mice concluded that flaxseed inhibited the growth of human estrogen - dependent breast cancer, and strengthened the tumor - inhibitory effect of tamoxifen.

Curcumin has been clinically shown to inhibit growth of various cancer cells including: Bone Cancer, Breast Cancer, Brain Tumors, Colon, Liver, Pancreatic, Stomach, Bladder, Kidney, Prostate, Leukemia, Ovarian, Melanoma, and more!

This finding was reinforced by an animal study, in which tocotrienol inhibited tumor growth in mice that had been injected with human liver cancer cells.

They compete with candida in the intestine, they suppress the growth of potentially harmful bacteria, they produce substances that can lower cholesterol, they enhance the protective barrier of the digestive tract, they help produce vitamin K, they improve immune function, they lower blood cholesterol in some people, they lower blood pressure in some people, they aid in the digestion of lactose, they prevent cavities, they decrease the passage of bacteria or antigens from the intestines to the blood stream, they fight pre-carcinogenic or mutagenic compounds, they lower the pH of intestinal contents, they utilize oxalate (oxalate contributes to kidney stones), they detoxify ingested carcinogens, they produce compounds that inhibit the growth of tumor cells, and more!

Inhibits the growth of tumors and cancer cells.