The researchers also showed that DENV NS1 caused similar levels of blood vessel leak in normal mice as in mice bred to have
inhibited cytokine activity, suggesting that cytokines were not necessary for this effect.
Not exact matches
He showed that engagement of PD - 1 by PD - L1 or PD - L2
inhibited T cell activation,
cytokine production, and cytolytic
activity whereas blockade enhanced these
activities.
It also tends to act in the body's production of IL - 10 if it is taken during infection, downregulating the levels of other
cytokines and necessary, but if taken early in the disease process, it
inhibits viral upregulation of IL - 10 and increases antiviral
cytokine production and
activity.»
This is by virtue of its antioxidant
activity, which controls levels of
cytokines, proteins of low molecular weight that can stimulate or
inhibit cell recruitment to the airways.
Researchers found that HA
inhibited inflammatory
cytokine activity in mice with inflamed joints.18 A similar study reviewed the effects of HA on acute and chronic inflammation in rats, finding HA suppressed inflammatory reactions to aid healthy cartilage production.19
Curcumin has also been shown to
inhibit an inflammatory response from
cytokines, chemokines, adhesion molecules, growth factors, and enzymes, while also promoting the
activity of phase II detoxification enzymes.
Its novel mode of action specifically targets and
inhibits the
cytokines involved in itch and inflammation with minimal
activity against
cytokines involved in hematopoiesis or innate immune function.
In certain types of cancer, erythropoietin production by the kidneys, as well as its
activity on the bone marrow, is
inhibited by cancer - produced
cytokines (the substances that mediate inflammation) as well as by chemotherapeutic drugs.