Nicotine may also act as an anti-estrogenic compound,
inhibiting aromatase and one of the two estrogen receptors directly; this may underlie some of the side - effects associated with chronic usage of nicotine / cigarettes, particularly in women.
Part of the mechanism is by androgenic interference with the estrogen receptor (ER) and lowering circulating estrogen levels by competitively
inhibiting the aromatase enzyme.
While this cancer preventing effect is most important for women,
inhibiting aromatase in aging men has tremendous potential for naturally suppressing excess estrogen while boosting low levels of testosterone to a youthful state.
Grape Seed Extract (95 % Proanthocyanidin)(150 mg): Proanthocyanidin helps block the conversion from testosterone to estrogen via
inhibiting the aromatase enzyme and also promotes nitric oxide production.
Similarly to their estrogen lowering effects by
inhibiting the aromatase enzyme, both progesterone and Vitamin E also work by directly blocking estrogen receptors.
EstroQuench ™ is used by healthcare professionals to reduce estrogens levels by
inhibiting aromatase activity, which will decrease the conversion of androgens (testosterone and androstenedione) to estrogens (estradiol and estrone).
The generally recommended dose for
inhibiting the aromatase enzyme behind this process if around 80 mg a day.
The mineral zinc is also known to
inhibit the aromatase enzyme, so making sure to meet your daily requirements of zinc can be helpful for restoring normal levels of testosterone.
The combination of grape extract and physical activity offers more protection than physical activity alone 06.03.2018 Grape Seed Extract during menopause: fewer hot flushes, more muscle and better sleep 12.08.2015 Poo smells less with Grape Seed Extract supplement 08.08.2015 Slimming supplement containing ECGC, resveratrol and Grape Seed Extract shown to work in human study 12.01.2014 Grape Seed Extract speeds up damaged muscle tissue recovery 15.09.2013 Grape Seed Extract keeps big eaters» weight down 11.12.2012 Grape Seed Extract helps prevent swollen legs 06.08.2012 Grape Seed Extract inhibits «genetically inevitable» prostate cancer 14.07.2012 Resveratrol and Grape Seed Extract protect against skin cancer 02.03.2012 Red grape juice is a smart drug 18.11.2011 Gallic acid is the anti-cancer agent in Grape Seed Extract 12.11.2011 Grape Seed Extract protects against prostate cancer 11.11.2011 Grape Seed Extract protects against skin cancer 29.10.2011 Anti-cancer supplements like GSE need plant - based proteins to be effective 21.09.2011 Arginine with grape extract enhances condition condition 25.06.2010 Grape Seed Extract
inhibits aromatase & glucocorticoid receptor 05.08.2009
6 - OXO is an effective inhibitor of the enzyme aromatase; however, it does not completely
inhibit aromatase activities
Some vegetables may
inhibit aromatase, the enzyme used by breast cancer tumors to produce their own estrogen.
Aromatase and the increase in estrogen that it can produce has such a strong link to breast cancer that a medication to
inhibit aromatase is used to treat some breast cancers.
AE3 contains 500 mg of pure chrysin extract, combined with Bioperin to enhance bio-availability, to safely and effectively
inhibit aromatase.
In small amounts, DIM can
both inhibit the aromatase enzyme (and prevent conversion of testosterone into estrogen) and it can act on more potent forms of estrogen and convert them into less potent forms; this conversion reduces the overall effects of estrogen in the body.DIM also exerts numerous anti-carcinogenic (anti-cancer) effects in the body and is one of the reasons this vegetable family is seen as healthy.
Two recent studies have identified specific mechanisms by which chrysin
inhibits aromatase in human cells.
The compounds in green tea can
inhibit aromatase too, which is an enzyme that turns androgens (male hormones like testosterone) into estrogen.
Not exact matches
In animal and cell culture studies, the drug
inhibited growth both in estrogen - dependent breast cancer cells and in cells that had developed resistance to the anti-estrogen tamoxifen and / or to the
aromatase inhibitors, two of the most widely used types of drugs to prevent and treat estrogen - dependent breast cancer.
Without adequate amounts of zinc, the testicular cells lose the ability to convert lipids, concentration of androgen receptors decrease and levels of
aromatase in the liver are
inhibited.
Passionflower —
inhibits the action of
aromatase.
Studies show that nettle extracts do boost testosterone levels by
inhibiting the action of enzyme
aromatase that converts free testosterone to estrogen as well as binding with the Sex hormone binding globulin that arrests free testosterone.
The root extract have also been found to
inhibit enzyme
aromatase.
Stinging nettle root extract can rectify this by
inhibiting the process of aromatization (conversion of testosterone to estrogen by enzyme
aromatase).
For estrogen modulation, it features two
Aromatase Inhibiting compounds.
Dienogest, a synthetic progestin,
inhibits prostaglandin E (2) production and
aromatase expression by human endometrial epithelial cells in a spheroid culture system..
This study was performed specifically to test the
aromatase inhibiting ability of 6 OXO, its clinical safety, and to determine its effects on the hormone levels in the body.
When
aromatase is
inhibited, it follows that estrogen is also reduced, and there is a corresponding increase in testosterone.
These results suggest that
aromatase activity is not completely
inhibited by 6 - oxo during the 8 week trial period.
Supplementing 6 - OXO leads to significant increases in free testosterone, DHT, and also slight increases in estradiol and estrone (presumably from the fact that
aromatase activity is not 100 %
inhibited)
The citrus flavonone hesperetin
inhibits growth of
aromatase - expressing MCF - 7 tumor in ovariectomized athymic mice.
In the early 1980's it was found to have the ability to
inhibit the conversion of testosterone into estrogens by
inhibiting the enzyme called
aromatase.
They can be prevented by an
aromatase inhibitor which will reduce and
inhibit the body to bloat.
The study tested the
aromatase -
inhibiting effects of these natural flavonoids (such as genistein, rutin, tea catechins, etc.) in human fat cell cultures.
In a study published in the Journal of Steroid Biochemical Molecular Biology (1993; Vol 46, No 3), chrysin and 10 other flavonoids were compared to an
aromatase -
inhibiting drug (aminoglutethimide).
The scientists conducting the study concluded by stating that the
aromatase -
inhibiting effects of certain flavonoids may contribute to the cancer preventive effects of plant - based diets.
Flavonoids such as chrysin are of considerable interest because they suppress excess estrogen via their
aromatase -
inhibiting properties.
In lab studies, naringenin
inhibits enzymes that activate carcinogens and the
aromatase enzyme that stimulates estrogen production.