In the laboratory animal study, ursolic acid, the active compound in holy basil, combined with radiation was more effective at inducing skin cancer cell death and
inhibiting new tumors from forming than radiation alone.
Not exact matches
Maria Zajac - Kaye, Ph.D., an associate professor in the College of Medicine's department of anatomy and cell biology, and Rony François, an M.D. / Ph.D. student who works with her, found a
new drug combination that
inhibits one form of pancreatic cancer
tumor and kills its cells.
One form of pancreatic cancer has a
new enemy: a two - drug combination discovered by UF Health researchers that
inhibits tumors and kills cancer cells in mouse models.
Trebananib (formally known as AMG 386; Amgen) is a first - in - class peptide - Fc fusion protein (or peptibody) that targets angiogenesis (the growth of
new blood vessels into cancerous
tumors) by
inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.
As these compounds are already approved for clinical trails in pediatric brain
tumors, these findings suggest that drugs
inhibiting MEK activity could offer a
new therapy option for children with these devastating
tumors.
The researchers say these
new findings predict that a large proportion of Pten
tumors will be hypersensitive to Eg5 -
inhibiting drugs, providing
new opportunities for targeted cancer therapy.
The research could help determine which individuals are at greatest risk of developing lung
tumors that may be amenable to a
new therapy to
inhibit their progression.
This treatment
inhibits the formation of
new blood vessels that can help a
tumor grow.
For the
new study, they added a component to the model that simulates the
tumor's response to drugs that target VEGF and
inhibit its activity.
Earlier studies by Basu and others have shown that dopamine blocks the growth of
new blood vessels in
tumors by
inhibiting the action of vascular endothelial growth factor - A (VEGF - A).
«Researchers
inhibit tumor growth in
new subtype of lung cancer: Insight into
tumor suppressing and
tumor promoting mechanisms offers potential for
new treatments.»
All of these foods contain the inositol phosphate IP5 — a compound that even at low dose limits the supply of blood to
tumor cells and
inhibits tumor growth in mice, according to
new findings.
An open - source content management system then would search through upwards of a billion drug combinations to find those with the greatest potential to
inhibit a given
tumor, or a billion hypothetical compounds to identify candidates for
new drug development.
«Visualizing how cancer cells interact with a
tumor microenvironment that accurately reflects the complex biology of ovarian cancer should help us understand the mechanisms underlying metastatic progression as well as identify
new therapeutics that can
inhibit this process,» said clinical gynecologic oncologist Ernst Lengyel, MD, PhD, senior author of the study and a professor of obstetrics and gynecology at the University of Chicago.
Swanton's
new lab set out to identify specific genes that, when
inhibited, result in the death of
tumor cells that displayed aneuploidy, meaning they had more or less than the normal set of 46 chromosomes.
Fourth, vitamin C can
inhibit tumor angiogenesis, the process of
new blood - cell formation crucial to
tumor survival.
They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and
inhibiting the formation of
new blood vessels that nourish
tumor growth.
An understanding of mechanisms of metastasis has led to the development of
new treatments designed to delay or
inhibit tumor spread.