This explanation differs from the conventional theory that SSRIs directly relieve depression by
inhibiting the reabsorption of the neurotransmitter serotonin in the brain.
Dr. Shomron adds that the new explanation resolves the longstanding mystery as to why it takes at least three weeks for SSRIs to ease the symptoms of depression when they begin
inhibiting reabsorption after a couple days — the development of neurons and synapses takes weeks, not days.
These drugs
inhibit the reabsorption of serotonin, making it available longer for transmitting signals between neurons.
Not exact matches
Both drugs
inhibit reuptake, or
reabsorption, of these neurotransmitters by neurons, thus prolonging their action.
Coffee
inhibits this glutamate
reabsorption.