Sentences with phrase «inhibitory cell surface receptors»
In addition, exhausted CD8 T cells start to express inhibitory cell surface receptors that receive and feed inhibitory signals into the cell establishing a negative feedback loop.
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Without it, NFAT initiates a negative regulatory program that activates genes encoding inhibitory cell surfaces markers and blunts signals received by the T cell receptor.
Targeting these proteins may be superior to targeting cell surface proteins because their elimination confers simultaneous insensitivity to multiple cell - surface inhibitory receptors.