Interestingly, it has recently been shown that memantine, an uncompetitive NMDA receptor antagonist that inhibits overactivity of NMDARs, was able to prevent retinal ganglion cell degeneration in streptozotocin - induced diabetic rats [73].
Another interesting finding was that in performing the experimental task, the participants with TS also had overactivity in the frontal region when inhibiting a movement.