The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein
inhibits the signal transduction pathway of interferon gamma.
Not exact matches
Surprisingly, the application of larval oral secretions
inhibited the
transduction of calcium
signals to neighboring leaves in the experiment.
Growth of osteosarcoma cells was
inhibited by this drug by targeting of multiple
signal transduction pathways [41].
Furthermore, niclosamide
inhibited not only
signal transduction, but also targeted mitochondria in cancer cells resulting in cell cycle arrest, growth inhibition and apoptosis [49 - 51].
Signaling pathways were
inhibited in osteosarcoma and, especially, Wnt / β - catenin
signal transduction in ovarian cancer cells and via GSK3 and STAT3 in CSCs and colon cancer [41, 47, 50, 52, 53].
It also has shown that it may
inhibit inflammation
signal transduction and maintain steady levels of testosterone.