Sentences with phrase «initial clinical trials»

This dose was chosen based on previous in vivo studies (28, 29, 32), as well as the following dose - conversion formula, as provided by the U.S. Food and Drug Administration in Guidance for Industry: Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers: animal mg / kg dose × animal km = human mg / kg dose × human km (km = body weight [kg] / body surface area [m2]-RRB-.

In fact, researchers at Stanford are already collaborating on initial clinical trials of an antibody that blocks cancer cells from displaying one such death - evading signal — a molecule called CD47.

This vaccine has moved through initial clinical trials in the U.S. and is now being tested in South Africa, which has one of the largest burdens of TB in the world.

Friedman and colleagues are now in discussions with pharmaceutical companies to move the vaccine, or an optimized version of it, into initial clinical trials.

The researchers noted that initial clinical trial data have been validated in larger phase II trials in the setting of relapsed / refractory HL, non-Hodgkin's lymphoma (NHL), and multiple myeloma (MM).

Initial clinical trials of VBP15 are planned, pending Food and Drug Administration (FDA) review and approval, anticipated in 2014.

The treatment has made it through initial clinical trials; now, the company hopes to speed the drug's time to market by labeling Ketasyn a medical food.

In the NEJM study from Dunbar and colleagues, the antibody had similar effects in an initial clinical trial in 83 people, lowering the blood levels of triglycerides measured after fasting by about 75 percent at the highest dose, and lowering LDL cholesterol by about 30 percent.

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

In an initial clinical trial involving a handful of people with HIV, levels of the virus circulating in the blood decreased — becoming undetectable in one person.

The researchers have not yet released the results of their phase II initial clinical trials, but Shima says that in the patients with haemophilia they looked at, bleeding frequency decreased dramatically.

In the initial clinical trial, the researchers tested their method in three patients with CLL.

Initial clinical trials were carried out on a small number of glaucoma patients and compared with tests on healthy people.

The initial clinical trials established the safety of the test for patients.

Led the initial clinical trials that established temozolomide (Temodar) as the current standard of care for glioblastoma

Sep 14, 2016 ISCoS meeting 2016 Initial Clinical Trials of hESC - Derived Oligodendrocyte Progenitor Cells in Subacute Spinal Cord Injury