p. 12 «Because dogs older than 14 - 16 wk of age are not likely
to have interfering levels of MDA [maternally derived antibodies], administration of a single
initial dose of an infectious
vaccine to an adult dog can be expected
to induce a protective
immune response.
In dogs it has been demonstrated that when intranasal Bordetella bronchiseptica
vaccines are used for
initial vaccination and injectable
vaccines are used for subsequent doses,
immune responses may be improved.3, 4 Similar techniques combining oral and injectable
vaccines have been demonstrated
to provide a more robust
immune response in humans.5 Zoetis is excited
to be the only company
to offer veterinarians the capability
to use this concept for vaccination of their canine patients against B.bronchiseptica.