Sentences with phrase «initiating early phase»

The Brain and Spinal Tumor Program at the Kimmel Cancer Center is a member of the Adult Brain Tumor Consortium (ABTC), a group of 16 medical centers dedicated to improving treatments for adults with malignant brain tumors by initiating early phase clinical trials and collaborations with researchers and other clinical trials groups.

Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma

Not exact matches

With approximately two - thirds of responders to AF - 219 treatment showing more than a 50 % reduction in cough frequency, we plan to advance the development of AF - 219 by initiating a Phase 2b study in patients with chronic cough early next year and to initiate other studies in preparation for registration studies.»

These results support Afferent's current development strategy to initiate a Phase 2b clinical trial early in 2015.

They initiated their Phase 1 BIIB054 trial in 2015, and reported promising early results of its use in an animal model of Parkinson's back in the summer of 2016, but have never published the results, issued press releases, or held conference calls to share their findings with the wider public.

Investigators led by Edward S. Kim, MD, of MD Anderson Cancer Center in Houston, initiated the SELECT trial after earlier, phase II studies showed that cetuximab improved response rates when added to chemotherapy regimens for patients with recurrent or progressive NSCLC.

A Phase I clinical program to assess safety and tolerability with investigational compounds was initiated in early 2014.

Whereas earlier RCTs of cognitive behavioural interventions studied individuals diagnosed with ASD, and were initiated within one month of the traumatic incident, 1 this study reduced the intervention length, started treatment at a later post-trauma phase (5 — 10 weeks), and did not require a diagnosis of ASD for inclusion.