Doctors now have limited means of repairing cartilage: They can graft or
inject knee cartilage cells from a cadaver or a healthy part of the person's own joint.
Not exact matches
When RCGD 423 was applied to joint
cartilage cells in the laboratory, the cells proliferated more and died less, and when
injected into the
knees of rats with damaged
cartilage, the animals could more effectively heal their injuries.
After tracking the
injected cells in the mice for more than 10 days using bioluminescence and fluorodeoxyglucose (FDG)- positron emission tomography (PET) imaging, they found that the injection of the senescent cells into the
knee region caused leg pain, impaired mobility and characteristics of osteoarthritis, including damage to surrounding
cartilage, X-ray changes, increased pain and impaired function.