«Surprisingly, the influence of lymph on the protein corona and the fate of nanoparticles has so far been completely neglected — although subcutaneously
injected nanomedicines immediately contact the patient's lymph,» says Mioni?
In fact, the mice that received the complete
nanomedicine package had smaller tumors and longer lifespans than their counterparts
injected with saline, nanoparticles without the drug, the drug alone, and nanoparticles with the drug but without the targeting aptamers.