Not exact matches
But when the mutant
mice were
injected with about 200,000 stem cells directly into their hippocampi and retested up to three months later, the injured animals performed up to par with their
normal counterparts.
Her team took purified extracts of the miRNA from stressed
mice and
injected them into
normal embryos.
He and colleagues at the University of California, San Francisco,
injected the brains of
mice with prions they had created in the lab by misfolding
normal prion protein, known as PrP.
Mallat hopes to clarify the role of regulatory T cells with a new experiment:
injecting the cells into genetically
normal mice with atherosclerosis, to see whether the cells can treat the disease.
They then
injected the protein into elderly
mice with
normal immune systems, and found this reproduced the beneficial effects of cord plasma on both memory performance and LTP in the hippocampus whereas
mice engineered to lack TIMP2 showed reduced LTP.
They
injected both the knockout
mice and
normal mice with AAV vector and found that 33 % -56 % had liver tumors, compared to 4 % -8 % of untreated
mice.
To validate their findings, the scientists
injected the novel nanoparticles into pancreatic tumor - bearing
mice and observed that by balancing these two targets — bringing them to a
normal level by increasing their expression or blocking the gene responsible for their expression — they significantly prolonged the survival of the
mice.
In the latest study, the researchers
injected the nine miRNAs into zygotes from
normal mice, implanted the zygotes in females, and allowed them to mature.
But when researchers used that sperm to fertilize eggs in the lab that were then
injected into female
mice, the
mice birthed pups at a
normal rate.
For prevention studies, they
injected mouse α - syn synthetic preformed fibrils into wild - type,
normal mice, as a control, and then immediately treated the
mice with Syn303, one of the MAbs used (or IgG, another type of common antibody, for the control
mice).
Kipnis and his colleagues wondered how smart
mice would be if they had a
normal supply of T cells everywhere in their bodies except the meninges, so he
injected a compound into
mice that prevented T cells from reaching the meninges.
«However, a single dose of copper
injected into
mice within a few days of birth restored
normal growth and life expectancy.
Normal mice do not develop disease if
injected with human prions, presumably because the human prion binds only to human PrP.
The researchers were also able to turn
normal - birthweight pups into obese
mice by
injecting extra leptin 5 to 10 days after birth.
When the researchers
injected extra copies of the betatrophin gene into the liver of
normal mice, the animals» pancreases responded by making as much as 30 times more β cells than usual.
To circumvent this delay, scientists
inject cattle tissue into «wild - type,» or
normal,
mice to see if they develop the disease.
They found that the cone function and morphology in
mice that had been
injected at 14 days were nearly
normal, and that the function and morphology of the surviving cones in the
mice that had been
injected at 90 days had improved — and the number of functioning cones had increased.
Young said Celltex did a study in which it
injected lab
mice with 73 times the
normal dose of 200 million cells that Celltex gives its clients, and none of the
mice died, developed toxic organs or grew tumors.
This early hint that age - related changes in EP2 action in microglia might be promoting some of the neuropathological features implicated in Alzheimer's was borne out in subsequent experiments for which Andreasson's team used
mice genetically predisposed to get the
mouse equivalent of Alzheimer's, as well as otherwise
normal mice into whose brains the scientists
injected either A-beta or a control solution.
We will
inject these
mice with either oxidized proteins, bacterial components, or
normal saline in a single injection when they are young.
To do so, they
injected melanoma cells into the bloodstream of
normal or E2 mutant
mice and monitored lung metastasis.
Cells with
normal karyotype were
injected into blastocysts isolated from C57BL / 6
mice.