We have shown that invariant Natural Killer T cells (iNKT), a subset of CD1d - restricted T cells displaying
innate effector functions, rewire the prostate cancer microenvironment leading to cancer control.
Besides their well - known
function as
effector cells in allergic responses, mast cells were reported to play a critical role in
innate immunity and to exert important stimulatory but also suppressive
functions in adaptive immune responses.