With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions,
innate immune control of adaptive immunity, tumor infiltration by immune cells).
Not exact matches
Innate immune cells
control the immediate response to an infection, including neutrophils and macrophages, Curtis explained.
The UNC research team, led by Lemon and Jason Whitmire, Ph.D., Associate Professor in UNC's Department of Genetics, is now poised to investigate the complicated interplay of nonspecific «
innate» and specific «adaptive»
immune responses that ultimately
control the infection and eliminate HAV from the host — processes that are not well understood for any of the five human hepatitis viruses.
These receptors detect viral RNA and signal an
innate immune response inside the cell that is essential for limiting and
controlling viral infections.
New research shows that all - trans - retinoic acid (atRA), the active form of vitamin A, regulates
immune system responses in the mouse intestine by
controlling expression of the protein HIC1 in cells known as
innate lymphoid cells.
The researchers found glucocorticoids tightly
control bacteria - induced
innate immune and inflammatory response by enhancing IRAK - M, one of the most critical negative feedback regulators of inflammation that inhibits the activation of the proteins MyD88 and IRAK1 / 4.
Based on empirical data obtained in cases of chronic myeloid leukemia, a myeloproliferative syndrome
controlled by the
immune system, and in solid tumors, we observe both the possible contribution of
innate CD8 (+) T cells to cancer disease
control and their susceptibility to tumor
immune subversion.
Noncytolytic
control of viral infections by the
innate and adaptive
immune response.
In a study appearing online February 8 in advance of publication in the March issue of the Journal of Clinical Investigation, Gallo and his colleagues look at how the
innate immune system is
controlled in the skin, and find that genes
controlled by active vitamin D3 play an essential role in the process.
NK cells are one of the
innate immune systems «first responders» that help to
control an infection while the adaptive
immune responses are gearing up.