Sentences with phrase «innate immune defense»

«They endure numerous strains of pathogenic bacteria in their saliva and recover from wounds inflicted by other dragons, reflecting the inherent robustness of their innate immune defense.»

Toll - like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.

Not exact matches

The discoveries reported in two independent studies in the American Journal of Human Genetics on January 7 add to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection.

The innate immune system is the first line of defense in cells, and normally distinguishes molecules that belong to the body from foreign, disease - causing, molecules.

The innate immune response constitutes the first line of defense against invading microbes and plays a role in inflammatory disease.

«The first line of defense of the immune system, the innate immune response, is not acting quickly enough to clear the virus,» says co-lead author Gülsah Gabriel, a virologist at the Heinrich Pette Institute, Leibniz Institute for Experimental Virology in Hamburg, Germany.

Areas covered range from basic studies into the biology of innate and adaptive immunity (immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology) to immune contributions to health and disease (host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency).

Looking for an answer, Emerman and colleagues homed in on the immune protein TRIM5α, one of several proteins involved in innate immunity, the body's first line of defense against viral infection.

Furthermore, the immune response was simplified to a few antimicrobial proteins, such as lysozyme, which acts as the innate line of defense against infection.

Since this amoeba possesses an innate defense system similar to that of humans, while being genetically modifiable, the researchers can therefore carry out experiments on it in order to understand and fight genetic diseases of the immune system.

They focused on the innate immune system, a first - line of defense.

Innate immune signaling is known to stimulate ROS production, which participates in cell defense.

The innate immune system is the body's first line of defense, providing broad protection as opposed to the specific immune system which targets the specific threat.

The main mechanism includes phagocytosis of macrophages which play a critical role in nonspecific defense (innate immunity) and, moreover; they have a role as antigen presenters which also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes.

Further, cellular defense mechanisms, such as the innate immune responses are mainly directed outwards to protect the organism against irritants, pathogens, or injured cells.

Warner Greene, MD, PhD, director and senior investigator of GIVI, co-director with Volberding of the UCSF - GIVI Center For AIDS Research (CFAR), and one of the amfAR Institute's four project directors, said the team's strategy would focus on stimulating the less specialized, «innate» immune system that forms the first line of defense against infections.

NADPH oxidase as a critical regulator of host defense, inflammation, and injury Innate immune responses in the tumor microenvironment

The CAMP gene itself is also the subject of much study, as it has been shown to play a key role in the «innate» immune system, the body's ability to fight bacterial infection and the 1st line of defense.

The best defense, however, is to call the police, and as long as the police force isn't tied up dealing with a riot somewhere else in the system, the innate immune system has officers on patrol.

In gluten sensitivity, the innate immune system — an older part of the immune system and the body's first line of defense against invaders — responds to gluten ingestion by fighting the gluten directly.

Macrophages embedded in the GALT are part of the innate immune system, or the non-specific, first line of defense against infection (Fasano, 2011; Yu & Yang, 2009).

The T2R defense system continues in our respiratory system, where taste receptor cells have been shown to monitor the bacteria in our tissues and initiate an innate immune response if pathogenic species are detected.

Lactoferrin is part of the innate immune system, the first line of defense to protect us from infection.1 Because of this, it has antibacterial, antifungal, and antiviral properties.2 It has also been shown to support bone formation.3, 4 Lactoferrin looks promising in the support of breast cancer.5

When a healthy person gets sick, the body has a natural immune response which triggers the first line of defense (innate immune response) that then call the second line of defense (adaptive immune response) into action and raise the antibody response.

From this perspective, social adversity and perceived threat in childhood should upregulate the innate immune system, a system that provides immediate defense against infection, and enhance pro-inflammatory response tendencies as a way to prepare for potential impending tissue damage and infection.