Not exact matches
[1, 9] The unique blend of fatty acids in the breast milk has been linked to the
development of
innate and adaptive
immune regulation.
She is investigating the role of glycosylated molecules in tumor progression and metastasis, tissue - and species - specific expression of lectin receptors that play a role in regulating host
innate immune responses and inflammation, and the immunological mechanisms underlying chronic inflammation and cancer
development.
Areas covered range from basic studies into the biology of
innate and adaptive immunity (
immune cell
development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology) to
immune contributions to health and disease (host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency).
Through the use of powerful genomic techniques, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have found that the
development of
immune cells, called
innate lymphoid cells (ILCs), gradually prepares these cells for rapid response to infection.
Continued research could lead to a better understanding of how diet and nutrition affect
immune function, and possibly lead to the
development of therapeutically useful natural compounds that could boost the
innate immune response, the researchers said in their report.
In models lacking NLRX1,
innate immune cells called macrophages produce higher levels of IL - 6, a signaling molecule that has a central role in colorectal cancer
development.
The range of subjects includes, but is not limited to,
immune cell
development and senescence, signal transduction, gene regulation,
innate and adaptive immunity, autoimmunity, infectious disease, allergy and asthma, transplantation, and tumor immunology.
Interleukin 15 (IL - 15) regulates the
development, survival, and functions of multiple
innate and adaptive
immune cells and plays a dual role in promoting both tumor cell growth and antitumor immunity.
His current research interest at University of Rochester focuses on the molecular biology, pathogenesis,
innate immune responses and vaccine
development for RNA viruses, mainly arenaviruses and influenza.
Less supportive and more harsh parenting should accelerate speed of
development (Belsky et al., 1991; Figueredo et al., 2005) and lead to shifts in the
innate immune system to better respond to a harsh interpersonal environment.