Sentences with phrase «innate immune mechanisms»

When digestive remnants that are foreign to the body overload the usual mechanisms for trapping and breaking them down in the gut, innate immune mechanisms mobilize to recycle them.

Prior to joining Helmsley, Garabet was an assistant professor in the Immunology Institute at the Icahn School of Medicine at Mount Sinai where he led a research team investigating the implication of innate immune mechanisms in IBD, Crohn's disease, colorectal cancer, and other gastrointestinal disorders.

The logic is indirect, autophagy is a key innate immune mechanism against intracellular pathogens and protein restriction upregulates autophagy.

Not exact matches

She is investigating the role of glycosylated molecules in tumor progression and metastasis, tissue - and species - specific expression of lectin receptors that play a role in regulating host innate immune responses and inflammation, and the immunological mechanisms underlying chronic inflammation and cancer development.

By genetically modifying the social amoeba Dictyostelium discoideum, the microbiologists from UNIGE are able to conduct all sorts of experiments on the mechanisms of the innate immune system.

The innate immune system refers to the front - line defenders — the cells and molecular mechanisms that attack pathogens.

First, the innate immune response, the mechanism whereby the fly attempts to kill, isolate or neutralize the invading microbe.

Our experts in mucosal vaccine delivery have established in vitro and in vivo models to assess the activity of adjuvants and vaccine formulations on innate and adaptive immune cells, as well their capacity to stimulate different effector mechanisms of clearance.

The main mechanism includes phagocytosis of macrophages which play a critical role in nonspecific defense (innate immunity) and, moreover; they have a role as antigen presenters which also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes.

After working on innate immune signaling at a Biotech startup company she studied mechanisms of signaling specificity as a postdoc in Dr. Alexander Hoffmann's laboratory at the University of California, San Diego before joining the Molecular Cell editorial team in 2013.

Further, cellular defense mechanisms, such as the innate immune responses are mainly directed outwards to protect the organism against irritants, pathogens, or injured cells.

The discoveries of the three Nobel laureates have revealed how the innate and adaptive phases of the immune response are activated and thereby provided novel insights into disease mechanisms.

This new marker of senescent cells is recognized by a naturally occurring IgM antibody that belongs to the innate immune system and is likely to be involved in a natural mechanism of immune recognition and clearance of senescent cells.

Deborah A. Fraser Ph.D. (University of Wales, Cardiff) Investigating molecular mechanisms of the innate immune response.

College Park, MD (Scicasts)-- Researcher has uncovered a mechanism by which the bacteria that causes Lyme disease persists in the body and fights your early, innate immune responses.

She also investigates the cellular and molecular mechanisms of innate and adaptive immune responses by RNA vaccines.

Dr. Locksley's laboratory focuses on tracking cytokine expression in model systems, as a mechanism to investigate complex functional interactions between innate and adaptive cells in the immune system.

And so that's one of the other mechanisms of inflammation damage is an innate immune response.

Zonulin evolved as an adaptive mechanism to flush out microorganisms as part of the innate immune response against bacterial colonization of the small intestine (Fasano, 2011).

A different immune mechanism, the innate immune response, comes into play in reactions of gluten sensitivity, as opposed to the long - term adaptive immune response that arises in celiac disease.