Previously we showed that
the innexin unc - 7 gene is essential for coordinated locomotion in C. elegans [9].
Not exact matches
Therefore, part of the characterization of the
Unc - 7 phenotype involves understanding how ectopic gap junction channels arise in the absence of the
UNC - 7
innexin, and whether or not these ectopic neuronal connections contribute to the
Unc phenotype.
Like
unc - 7S:: gfp, this construct rescued forward locomotion in the absence of cosmid F56B12, and we postulated that M121 in exon IV (the canonical
innexin start site) might be used to generate a shorter but functional
UNC - 7S - like product (
UNC - 7SR).
unc - 7 encodes three
innexin isoforms.