In normal cells, very little of the target lipid could be detected when the toxin was
inserted into the cells, meaning the lipid was being flipped and immediately consumed by the toxin.
The antisense genes were
inserted into the cells» nuclei by a modified lentivirus that had been crippled to ensure it was incapable of reproducing.
They pick up fluorescent signals from particles
inserted into cells and tissues that are illuminated with specific wavelengths of light.
In addition, they developed a specialized infection apparatus, the polar tube, which they use to
insert themselves into the cells of their host.
Doing the screen involves using short pieces of RNA, called small hairpin RNAs, which are
inserted into the cell and are able to halt messages from specific genes, keeping the genes from making proteins.
The researchers found that CtBP can cause normal human cells to become cancerous when
inserted into the cell's DNA.
«Once inside the cell, cadmium
inserts itself into the cell's metal sensing machinery causing it to malfunction and pump out the wrong metal ions while still bringing in more cadmium.
Gene therapy offers the possibility of replacing the function of the defective or missing gene with that of a therapeutic gene
inserted into the cell.
One strategy scientists have developed is to engineer proteins to serve as tiny research tools that can be
inserted into the cell.
The material Jiang and colleagues developed is one - half of an electronic device that spontaneously creates itself when one of the silicon particles is
inserted into a cell culture, and eventually, the body.
Molecules of curcumin
insert themselves into cell membranes and make the membranes more stable and orderly.
Researchers have found that curcumin molecules
insert themselves into cell membranes making them more stable and orderly.
Not exact matches
Basically, CAR - T therapy involves taking a patient's own immune «killer» T -
cells,
inserting new genetic code
into those
cells which turn them
into cancer - hunters that can home in on malignant B -
cells (another kind of immune
cell), and then pumping these specialized leukemia - busting
cells back
into the patient.
Immune
cells modified by CRISPR - Cas9 were
inserted into a lung cancer patient at the West China Hospital in Chengdu in the hopes that they'll be able to fight tumors, and 10 people total will receive injections of CRISPR re-engineered
cells in order to assess the method's safety.
Researchers from the Sichuan University in Chengdu
inserted the re-engineered
cells into a lung cancer patient participating in a clinical trial at the West China Hospital on October 28th, according to Nature.
Science has
inserted a synthetic copy of DNA
into a living
cell membrane.
I'm amused your critique was that it was an existing parental
cell, because mine was that it was an existing (but modified) genome
inserted into it.
The
cell nuclei are removed from both sets of embryonic
cells, as shown in the diagram, the donor's nuclei and the remains of the parents» embryo are destroyed and the parents» nuclei are then
inserted into the donor or «host» embryo, still containing its healthy mitochondria.
Well, if you put a few brain
cells to work it's quite possible to realize there are other sayings associated with OMG like «Oh My Goodness» and «Oh My Gosh»... It's very possible to not always
insert «God»
into it... Just saying...
Like attempting to
insert religion
into the school system, stymie medical research aka stem
cells, restrict a woman's reproductive rights... etc..
They tested this by
inserting mutations
into the KRAS gene in the DNA of
cells exposed to the cigarette smoke condensate for six months as well as those exposed for 15 months.
The scientists found that the
inserted mutation transformed
cells into cancer in only the 15 - month
cells, where methylation was fully established, but not in the six - month - exposed
cells.
The researchers
inserted 25 foreign genes
into the one -
celled fungus to turn it
into an efficient factory for producing the drug.
As reported in Nature in May, the team
inserted the two
into a bacterial
cell, a strain of E. coli.
A viral epitope
inserted into the complementarity - determining region 3 (CDR3) loop of the heavy chain of a self immunoglobulin (Ig) molecule was generated from the Ig context and was presented by I - Ed class II molecules to virus - specific, CD4 + T
cells.
This DNA will
insert randomly
into the DNA of the
cells, disrupting any gene it happens to hit.
In 2006, he used retroviruses to
insert four genes
into the chromosomes of mouse skin
cells.
The researchers — James Robl, a developmental biologist and his colleagues at the University of Massachusetts at Amherst, and Steve Stice at Advanced
Cell Technology in Worcester, Massachusetts —
inserted a marker gene fused with a gene for resistance to the chemical neomycin
into a culture of connective tissue
cells called fibroblasts.
The
cell was created by stitching together the genome of a goat pathogen called Mycoplasma mycoides from smaller stretches of DNA synthesised in the lab, and
inserting the genome
into the empty cytoplasm of a related bacterium.
But scientists say they may one day be able to
insert microscopic carbon nanotubes
into injured joints — such as knees — encouraging new, stronger cartilage
cells to grow in place damaged or thinning ones.
Scientists from Harvard University, the University of Pittsburgh, and the University of Missouri at Columbia devised another solution:
inserting into pig
cells a gene that codes for an enzyme that converts omega - 6s to omega - 3s.
Using their nuclei to exert force, they
insert themselves between — as well as
into — the
cells (called endothelial
cells) in the vessel walls.
When the modified genome was
inserted into the recipient
cell it was immediately recognised and degraded.
The modified
cell nuclei were then
inserted into unfertilized eggs to create engineered pig embryos, which were implanted in a normal sow.
«With Rudolph,» Farber says, «the coral DNA got
inserted into a gene that is normally expressed in the nasal epithelial
cells, the
cells of his nose.
«We're looking at bacteria that make magnetic nanoparticles, so we can
insert their genes
into brain
cells in the same way,» Pralle says.
The first step in the process involves
inserting into those brain
cells a gene that makes a light - sensitive protein.
A membrane — designed to support the cultivation and differentiation of human nasal epithelial stem
cells — was
inserted into a small chamber on the device and fresh or contaminated air was fed through a tiny channel.
Next, a copy of the homing endonuclease gene with its surrounding DNA
inserts itself
into the gap as the
cell heals the breach.
The team
inserted this «magnet»
into mouse embryonic stem
cells, next to a gene that promotes a protein called p16.
After fishing stem
cells from each individual's own blood, the researchers
inserted a normal version of the ABCD1 gene
into some of the
cells and transplanted them back
into the kids.
Oncologists William Hahn, Robert Weinberg, and colleagues at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, mutated the gene for one part of the enzyme and
inserted it
into cultured human
cells from colon, ovary, and breast tumors.
Next, the team
inserted a gene that makes a light - sensitive protein
into the
cells of the arcuate sulcus.
The nuclei are
inserted into egg
cells which have had their original nucleus removed, a process called nuclear transfer.
This is the idea of
inserting a gene
into cells and that gene is light controlled, so that you can use light to manipulate the
cell.
When the scientists
inserted human colorectal cancer
cells into zebrafish embryos and allowed them to grow for 4 days, the resulting tumors showed three hallmarks of human solid tumors: rapid
cell division, formation of blood vessels to supply nutrients, and the ability to spread to other locations in the body.
One day, doctors might be able to
insert such devices
into a cancer patient to tally how many times a
cell divides and flag when to shut the cancer down.
In one such study by Ronald Evans and colleagues, the gene for rat growth hormone is stably
inserted into mouse
cells by a retrovirus.
The process enables some viruses to
insert their genetic material
into the DNA of healthy human
cells, which can lead to tumors and other diseases.
After just a single dose, rat intestinal
cells pumped out bacterial lactase for up to 6 months — showing that the gut
cells had
inserted the gene
into their DNA and were using it to manufacture the enzyme.