Sentences with phrase «inside macrophages»
The researchers showed that this protein buildup inside macrophages results from problems with the waste - disposal functions of the cell.
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By investigating the changes in Salmonella protein abundances during infection by Salmonella, the researchers identified a novel protein that is required for Salmonella to replicate inside macrophages.
Source: «Proteomic analysis of Salmonella enterica serovar Typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar Typhimurium inside macrophages.»
Results: Scientists at Pacific Northwest National Laboratory (PNNL) have reported the first systematic investigation using global proteomics to identify changes in the abundance of bacterial proteins associated with macrophage colonization and a new protein that helps the bacterium to survive inside macrophages.
Specifically, the new study found that TB bacterial proteins trigger an immune signaling pathway inside macrophages, where a protein complex called NFKappaB triggers a key gene to make more of microRNA - 33.
Not exact matches
Consequently, they discovered that by blocking Nrp1, macrophages were no longer able to migrate inside hypoxic regions in the tumor.
These investigations take advantage of white blood cells, monocytes, and macrophages that can target an inflammation site, including inside the brain.
TAIL TATS When researchers tattooed mouse tails, the only cells found with ink inside were macrophages.
They grow as extracellular parasites inside phlebotomine sand flies that transmit Leishmania to variety of vertebrates, such as rodents, dogs, and humans, where they grow inside immune cells, notably macrophages, causing severe pathologies that may lead to death.
In this study, the researchers found that macrophages from mice lacking Smurf1 were unable to attach the death - tagging protein ubiquitin to intracellular bacteria, resulting in a failure of the autophagy pathway and runaway growth of the bacteria inside the cells.
As expected, waste DNA piled up inside the animals» macrophages.
C. gattii not only can kill macrophages, they can also hide inside them.
The researchers focussed on the ability of trehalose, a sugar consisting of two linked glucose molecules, to increase the amount of organelles inside specialized «housekeeping» cells known as macrophages.
The bugs then take up residence inside cells of the immune system called macrophages.
The UVA researchers were able to «engraft,» or establish, immune cells known as macrophages inside the brains of lab mice without the need for radiation.
The paper, Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia, will be published in the journal Nature Microbiology.
So, vitamin C binds to receptor sites on the macrophage and helps with uhm — you know, the stress of dealing with infections or you're — you're basically little pacmen and women gobbling up crap inside your blood stream.
Sometimes the node is simply caught up in surrounding inflammation but some infectious organisms protect themselves by living inside lymphocytes and macrophages.