Like PM10 particles, they insinuate
themselves inside the walls of blood vessels, which can trigger the formation of the artery - clogging plaques that are the culprits behind strokes and heart attacks.
A specific lung - targeting molecule is attached to the carrier's surface and the steriod, dexamethasone, an anti-inflammatory, is loaded into the nanogel, which then binds to lung endothelial cells lining
the inside wall of the blood vessels where it rapidly delivers the drug.
There are multiple factors that can cause inflammation and damage of the endothelium, the layer of cells that form
the inside wall of every blood vessel in your body:
Not exact matches
When cancer cells interact with the
walls of the
blood vessels, EPHA2 is activated and the tumour cells remain
inside the
blood vessels.
When this happens, cholesterol can be deposited in
blood vessel walls, causing a narrowing
of the lumen (
inside)
of vessels, which can inhibit the supply
of blood to the heart or other organs and tissues
of the body.
Over time, too much glucose in the
blood can lead to increased plaque deposits on the
insides of the
blood vessel walls.
According to the U.S. Department
of Health and Human Services, «High
blood glucose levels over time can lead to increased deposits
of fatty materials on the
insides of the
blood vessel walls.