These efforts eventually blossomed into a highly productive program in comparative genomics that provided important
insights about genome structure, function, and evolution.
Not exact matches
By comparing our genetic make - up to the
genomes of mice, chimps and a menagerie of other species (rats, chickens, dogs, pufferfish, the microscopic worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster and many bacteria), scientists have learned a great deal
about how genes evolve over time, and gained
insights into human diseases.
Examining
genome sequence information for more than 250,000 people, the researchers first uncovered 16 new diabetes genetic risk factors, and one new CHD genetic risk factor; hence providing novel
insights about the mechanisms of the two diseases.
We provide initial
insights into two critical issues: what clinical value can be extracted from different commercial and academic cancer genomic platforms, and how to think
about scaling access to that value,» noted the study's Principal Investigator, Robert Darnell, MD, PhD, Robert and Harriet Heilbrunn Professor and Senior Attending Physician at The Rockefeller University and Founding Director of the New York
Genome Center.
The more we understand
about how natural variation in the vertebrate
genome shapes the development and function of the brain, the better
insight we can have into how behavioral patterns evolve, and how disruption to neurogenetic pathways can lead to brain and behavioral dysfunction.
The findings of this study will provide valuable
insight about how best to present information generated by whole
genome sequencing to optimize patient care and minimize the unnecessary use of limited healthcare resources.