Sentences with phrase «insulin secretion»

Several years ago we reported that protein, on a weight basis, is just as potent as is glucose in stimulating insulin secretion in persons with type 2 diabetes (14).

Osuna JI, Pages I, Motiño MA, Rodriguez E, Osorio C. Cephalic phase of insulin secretion in obese women.

It also helps increase insulin secretion in the pancreas, slows carbohydrate absorption, and increases a cell's ability to use glucose.

They also observed that infusions of acetate stimulated insulin secretion by beta cells in the pancreas, but it was unclear how.

Bethesda, Md. (January 10, 2018)-- A new study reports that chronic exposure to arsenic interferes with insulin secretion in the pancreas, which may increase the risk of diabetes.

With respect to blood sugar and insulin regulation, we have seen smaller scale studies showing reduced insulin secretion after a meal and improved regulation of blood sugar levels, but most of these studies have focused on the short - term situation following a meal rather than extended blood sugar regulation over weeks or months.

In the Danish participants, higher DNA methylation in their first sample was associated with higher insulin secretion ten years later.

Bordone L, Motta MC, Picard F, Robinson A, Jhala US, Apfeld J, McDonagh T, Lemieux M, McBurney M, Szilvasi A, Easlon EJ, Lin SJ, Guarente L. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells.

People with this genetic variant also displayed signs of decreased insulin secretion.

Addition of TNF ‐ α, IFN ‐ γ, and IL ‐ 1β significantly increased TIMP ‐ 1 secretion from hASCs, and also led to increased insulin secretion from islets co ‐ cultured with hASCs, while blocking TIMP ‐ 1 with a specific antibody reduced its protective effect.

Type 2 diabetes results from impaired insulin secretion combined with impaired insulin action, which is also referred to as decreased insulin sensitivity or insulin resistance (21).

The dates provide your body with natural sugars such as glucose, fructose, and sucrose for a burst of energy, while the coconut improves insulin secretion for stable blood sugar levels (translation: no sugar crash).

Their aim is to increase insulin secretion after food intake in people with type 2 diabetes.

Simon C, Schlienger JL, Sapin R, Imler M. Cephalic phase insulin secretion in relation to food presentation in normal and overweight subjects.

A higher concentration of indolepropionic acid also seemed to promote insulin secretion by pancreatic beta cells, which may explain the protective effect.

He hypothesized that the lower cholesterol levels in the violent offenders could be «a consequence of enhanced insulin secretion and that high insulin levels are responsible for violent behavior.»

The mode of action of this hormone is to increase insulin sensitivity of muscle and other tissues, which in turn lowers insulin secretion, because you don't need as much insulin to transport nutrients into your cells, if your cells are very sensitive to insulin.

Despite not developing IR, glucose intolerance can be induced in C57BL / 6 mice fed a high sucrose diet (50 % sucrose) relative to those fed a similar diet high in corn starch from 10 — 55 weeks, which has been attributed to a reduced pancreatic insulin secretion (14).

The fiber slows down the rate of digestion and absorption, so it doesn't cause spikes in blood glucose levels, and therefore it doesn't cause insulin secretion peaks.

Glucose toxicity occurs when insulin secretion is reduced by prolonged hyperglycemia.

Artificial sweeteners directly affect insulin secretion, subsequent blood sugar levels, and other unknown metabolic effects likely exist as well.

A regulated pulse of insulin secretion resulted in a transient correction of serum glucose concentrations in a mouse model of hyperglycemia.

In an analysis of data from 1003 subjects of the Tübingen Diabetes Family Study of whom 405 had prediabetes, the 4 at risk phenotypes insulin secretion failure, insulin resistance, fatty liver, and magnetic - resonance imaging (MRI)- determined visceral obesity, but not BMI category (normal weight, overweight, and obese) or visceral obesity based on waist circumference, were independent determinants of prediabetes.

Inherited insulin resistance in conjunction with environmental risk factors such as physical inactivity, obesity, and consumption of excessive amounts of highly refined, easily digestible carbohydrates places a large, prolonged demand on the β - cells for excessive insulin secretion, which eventually results in β - cell exhaustion and diabetes.

«What is remarkable about our findings is that they show that a simple dietary modification of reducing the carbohydrate content of the meals can, within a day, protect against development of insulin resistance and block the path toward development of prediabetes while sustained intake of high carbohydrate diets as shown in the two mentioned studies lead to increased fasting insulin secretion and resistance.

Type 2 diabetes in cats (Diabetes mellitus) is associated with defective insulin secretion, insulin resistance and various cell changes, including amyloid formation which occurs.

«Not only is this response likely to be helpful for proper insulin secretion but it also seems to hold back the death mechanisms that can be turned on when ER stress is really aggressive,» says Weir, who is co-head of Joslin's Research Section on Islet Cell and Regenerative Biology.

Because higher GLP - 1 responses are associated with better insulin secretion, the low incretin levels could partly explain the reduction of β - cell function observed in women when becoming IGM or T2DM.

They tend to have higher levels of insulin secretion over the course of a day and as result have excess body fat.

Insulin secretion goes back up to normal levels if that excess fat is eliminated.

Nevertheless, the possibility that eating during daylight hours results in less insulin secretion must be considered.

The naturally - leavened einkorn loaves significantly reduced the gastrointestinal response of GIP (glucose - dependent insulinotrophic polypeptide), a hormone important in controlling insulin secretion.

IFG is characterized by increased hepatic glucose output and impaired early insulin secretion, whereas IGT is primarily due to peripheral insulin resistance (82).

Under normal conditions functional compensation of insulin secretion significantly contributes to preventing the development of type 2 diabetes and gestational diabetes.

So if we know insulin resistance and inflammation's part of that underlying mechanism, doesn't it make sense to cut out the foods that are driving inflammation and cut out the foods that are driving insulin secretion, right?

Perhaps the amino acids stimulated the incretin pathway as a mechanism of glucose - independent insulin secretion.

Promoting healthy insulin secretion, which is imperative for optimal health.

This sugar — unlike most sugars — may help suppress insulin secretion.

This sweetener has been shown to stimulate insulin secretions even though it does not increase blood sugar (6).

Thus, a diet rich in refined grains and starches will prompt greater insulin secretion than a diet that is not.

This visual abstract depicts the Yoshihara et al. report that the postnatal maturation of pancreatic b cells necessary for maximal glucosestimulated insulin secretion is coordinated by the estrogen - related receptor g (ERRg).

Synthetic beta cells for fusion - mediated dynamic insulin secretion.

Pancreas tissue from older mice or from young animals subjected to sleep deprivation exhibited signs of protein misfolding, yet both were able to maintain insulin secretion and control blood sugar levels.