Sentences with phrase «integrin cell adhesion»

Not exact matches

«In our prior studies, tension gauge tethers with different tension tolerances were individually presented to cells, and we found the universal threshold force for integrin - mediated cell adhesion is around 40 pico - Newtons,» Roein - Peikar said.

The integrin - ligand bond activates cells» adhesion to a surface only when the DNA tether does not rupture, enabling a measurement to be taken of the molecular force.

This physical change causes adhesion receptors on the cell surface called integrins to clump together.

Alteration of collagen - dependent adhesion, motility, and morphogenesis by the expression of antisense a2 integrin mRNA in mammary cells.

Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class of cell surface proteins that function in the interactions of immune cells with other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune disease.

Our laboratory focuses on the molecular basis of cell adhesion to collagen with a focus on the alpha2 beta1 integrin.

BCR / ABL expression of myeloid progenitors increases beta1 - integrin mediated adhesion to stromal cells.

Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alphavbeta6 on porcine trophectoderm cells and integrin alphavbeta3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration.

Functional expression of CXCR4 (CD184) on small - cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells.

Expression of the receptor tyrosine kinase Tie2 in neoplastic glial cells is associated with integrin beta1 - dependent adhesion to the extracellular matrix.

Another interesting local network structure is centered around CLU, a gene shown to be involved in AD based on genome - wide association studies, with genes in the integrin family, involved in cell adhesion, clustered around CLU.

Specific mechanistic studies include an interrogation of the adhesion dynamics controlled by the tetraspanin CD151 and affiliated adhesion receptors (Integrins and IgG cell adhesion receptors).

Other studies have shown that a family of proteins called 14 -3-3 are involved in learning along with interesting cell adhesion molecules of the integrin family and the immunoglobulin superfamily.

The LG3 module of laminin - 5 harbors a binding site for integrin alpha3beta1 that promotes cell adhesion, spreading, and migration.

Shafaq - Zadah M, Gomes - Santos CS, Bardin S, Maiuri P, Maurin M, Iranzo J, Gautreau A, Lamaze C, Caswell P, Goud B, Johannes L (2016) Persistent cell migration and adhesion rely on retrograde transport of beta1 integrin.

Note added in proof: After completing our analysis, integrins and other cell - adhesion - related genes were discovered outside metazoa47.

Taken together, these results strongly suggest that the LPA2 signaling modulates T cell motility in the confined environments at least partly in an integrin - independent manner and may also act on cell adhesion to prevent over-adhesion to the substrates.