Canine hip dysplasia is a hereditary condition, but is brought on through
interaction with environmental factors.
At the moment, it is not clear whether the increased risk in some families is due to the type of mutation or to
interaction with environmental factors such as smoking.
Genetic epidemiology is a discipline takes care of studying the role of genetic factors and
their interaction with environmental factors in the aetiology of human disease.
Preclinical and clinical biomarkers must be discovered, and
their interaction with environmental factors understood, to then be validated in order, among other purposes, to refine the characterisation of phenotypes in heterogeneous diseases and to tailor the treatment to individual patients (personalised therapy).
Even classical Mendelian disorders have different clinical phenotypes that are a consequence of polymorphic or mutant disease ‐ modifying genes and
their interactions with environmental factors.
For instance, developmental studies of common dopamine (DA)- regulating gene polymorphisms and
their interactions with environmental factors, both positive and negative, were recently examined in meta - analysis by Bakermans - Kranenburg and van Ijzendoorn (2011).
Not exact matches
These results also suggest that the adjustment difficulties seen
with some children of divorced parents may be due to an
interaction between genetic and
environmental factors rather than
environmental influences alone, as is assumed in many theories of divorce» s effects.
Among the issues to be resolved there would be, for example, how to identify the
environmental factors that control the production of aggressive morphs; what costs and benefits
interaction involves for each participant; the taxonomic status of the deceit and the variability level in the chemical signal used for misleading ants; or what happens
with related aphid species which also relate
with ants.
«This is a very important discovery that will guide future research efforts to explore the
interactions of these pigmentary genes
with other genetic and
environmental risk
factors in cancers not linked to sun exposure, such as eye melanoma.
Above all, there is a new emphasis on the
interaction between vulnerable genes and
environmental triggers, along
with a growing sense that low - dose, multiple toxic and infectious exposures may be a major contributing
factor to autism and its related disorders.
Diagram indicating associations among genetic and
environmental factors reduce and their
interactions with intermediate phenotypes to yield distinct pathophenotypes.
Dr. Bailey - Wilson's research group seeks to understand the genetic
factors that increase risk for various complex diseases and their
interactions with environmental risk
factors.
Our team will spend time
with each person listening to their histories and looking into the
interaction of
environmental, genetic and lifestyle
factors that influence long term health and complex, chronic disease.
Celiac disease occurs from an
interaction between genes, eating foods
with gluten and other
environmental factors, but the precise cause isn't known.
Our physicians spend time
with their patients, listening to their histories, mapping their personal timeline, and looking at the
interactions among genetic,
environmental, and lifestyle
factors that can influence long - term health and complex chronic disease.
Contract Equity Professionals discuss the
interaction of personal dispositions
with behavioral and
environmental factors.
Type 2 diabetes has a complex etiology and is caused by a combination of genetic
factors and
environmental interactions, and risk increases
with aging (11,12).
You need to also know their market and generic name, what kind of
interactions they have
with other medications, diseases, and
environmental factors (tetracycline for example is photosensitive) and little facts like there's a limited number of antibiotics that you can give to pregnant women and what foods you can't eat if you're taking an antidepressant.
This range is a function of many
factors, including the specific area of deficit, the patient's
environmental response to and
interaction with the deficits, the therapy provided, and the presence of coexistent conditions.
Social and emotional learning (SEL) programming can be an effective way to reduce the likelihood of bullying because it promotes skills, behaviors, attitudes, and
environmental factors that are incompatible
with bullying and other forms of negative peer
interactions.
Functional variants of the MAOA - uVNTR, 5 - HTTLPR, and BDNF Val66Met, either alone or in
interaction with each other, may be best conceptualized as modifying sensitivity to
environmental factors that confer either risk or protection for teenage delinquency.
As a summary, we conclude that a strong genetic liability, in
interaction with parenting and relevant
environmental factors, can lead to elevated levels of CU traits; they can be detected in early childhood, may remain stable along the adolescence, but a possible decrease following intensive and specialized treatment is possible.
Generally, the results were similar to those of the GLM, although in the Poisson log - linear model the associations of delinquency
with the
interaction terms of sex and the two
environmental factors were not significant, whereas the sex × genotype
interactions were significant for all three genotypes.
Teenage delinquency was associated
with two -, three -, and four - way
interactions of each of the genotypes and the three
environmental factors.
Model predictors included main effects and
interactions of group
with linear and quadratic effects of time (i.e., time and time squared, respectively), and the three - way
interactions of 1 - year
environmental factors × group × linear time and
environmental factors × group × quadratic time.
A strong genetic liability, in
interaction with parenting and relevant
environmental factors, can lead to elevated levels of CU traits in children.
Environmental factors such as mother — child
interactions and family cohesion have also been linked
with internalizing disorders.