Microfabricated Channel Array Electrophoresis for Characterization and Screening of Enzymes Using RGS - G Protein
Interactions as a Model System.
Not exact matches
«This camera has the potential to greatly enhance our understanding of very fast biological
interactions and chemical processes that will allow us to build better
models of complex, dynamical
systems such
as cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.
«Liverworts are showing great promise
as a
model plant
system and this discovery that they can be colonised by pathogens of flowering plants makes them a valuable
model plant to continue research into plant - microbe
interactions.»
Systems biology research will aim to identify and validate mathematical
models that can accurately predict
interactions between immune
system components in relation to vaccination,
as well
as develop state - of - the - art methods for the structural and functional analysis of vaccine candidates.
The Polonis lab has also employed both cell line - based
model systems,
as well
as primary cell types from uninfected humans, to investigate virus - antibody - host cell
interactions and cross-subtype reactivities amongst the major subtypes of the HIV pandemic.
Mineralized human primary osteoblast matrices
as a
model system to analyse
interactions of prostate cancer cells with the bone microenvironment.
-- 7) Forest
models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8) Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adapt
models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8)
Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adapt
Models that account for
interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk
as a result of warming); 9)
Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adap
Systems thinking and
modeling regarding climate effects on understory vegetation and
interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support
systems to provide guidance for managing for adap
systems to provide guidance for managing for adaptation.
The study is commissioned by the U.S. National Geospatial Agency to help U.S. Department of Defense agencies understand and
model the
interaction of complex adaptive
systems such
as natural ecosystems, individual organisms, and human communities, organizations and families.
No matter how powerful the computer used or how impressive the
model output, any
model of a natural
system is only
as good
as the authors» understanding of the
interaction between the physical laws that define their subject and the potential of simple small - scale
interactions to produce large - scale complexity, more readily summarised
as:
Proposed campaigns should focus on research that addresses the ARM mission of improving the understanding and representation of clouds and aerosols in climate and earth
system models,
as well
as their
interactions and coupling with Earth's surface.
tomato
as this process results in bacterial speck, an economically important disease, and also serves
as a powerful
model system for understanding fundamental mechanisms involved in plant - pathogen
interactions.
Since the objective is a
model of all the
interactions in a
system, the experimental techniques that most suit
systems biology are those that are
system - wide and attempt to be
as complete
as possible.
Hale says that their
model of Charon / Pluto
interaction is valuable because it helps us look back in time at the chemicals present when our Solar
System was formed,
as Pluto hasn't had its atmosphere blasted away by either the extreme heat of the Sun or its solar wind.
Researchers use a variety of information and tools, such
as mathematical
modeling, to describe the complex
interactions among components of a biological
system and make predictions that help guide and further refine experimental science.
Dr. Locksley's laboratory focuses on tracking cytokine expression in
model systems,
as a mechanism to investigate complex functional
interactions between innate and adaptive cells in the immune
system.
Specifically to: 1) collaborate with Crittenton Women's Union (CWU) to create video resources that demonstrate its family skill - building
model as a means of building adult capabilities to improve child outcomes; 2) create an initial set of materials for practitioners and leaders of family service - provision
systems to be used with caregivers to improve serve - and - return
interaction as well
as self - regulation and executive function skills; and 3) test these materials
as part of a qualitative needs assessment of practitioners who wish to build the capabilities of adults who care for children birth - to - five, with an emphasis on birth - to - three.
However, current forecast
systems have limited ability on these timescales because
models for such climate forecasts must take into account complex
interactions among the ocean, atmosphere, and land surface,
as well
as processes that can be difficult to represent realistically.
The ARM Climate Research Facility, a DOE scientific user facility, provides the climate research community with strategically located in situ and remote - sensing observatories designed to improve the understanding and representation, in climate and earth
system models, of clouds and aerosols
as well
as their
interactions and coupling with the Earth's surface.
Actually the reverse is true: the more components we have, the more we will have to combine, the more
interactions there will be that we do not really understand, the more complex the
system becomes to undertand and
model as it seemingly acts independently of all the rules we developed that it is supposed to follow and refuses to obey.
Berkeley Lab researchers helped develop the first computational
model to accurately predict the
interactions between flue gases and a special variety of the carbon dioxide - capturing molecular
systems known
as metal - organic frameworks (MOFs).
While the primary contribution is in improving our ability to anticipate how earth
system interactions will modulate the rate of increase of carbon dioxide in the atmosphere, the fact that the
models require simulation of land and ocean ecosystems make them extremely valuable for a range of applications in ecosystem impacts and feedbacks
as well.
I
model the
system as being a complex mixture of interconnected parts with a myriad of different time constants affecting their
interactions.
That you have characterised their cause
as magnification of small changes by
system interactions doesn't rebut this view — time scale is a very slippery customer and finding the most accurate time fit for cycles of complex
interactions is likely to take much longer than 30 years (the preferred time grab so far for AGW
modeling)
Using atmospheric general - circulation
models,
as well
as coupled ocean - atmosphere
models, he investigates the
interactions between large - scale climate
systems such
as ocean and wind currents to understand natural variability and how climate responds to human - made forcings.
The ability of dynamic
models to capture various
interactions of complex
systems, their potential to adapt and evolve as the real system changes and / or the level of the modelers» understanding of the real system improves, their ability to model coupled processes of different temporal and spatial resolutions and scales, and their flexibility to incorporate and / or couple to models based on other approaches (such as agent - based modeling, stochastic modeling, etc.) render them as a versatile and efficient tool to model coupled Earth — Human Systems [190,191,19
systems, their potential to adapt and evolve
as the real
system changes and / or the level of the modelers» understanding of the real
system improves, their ability to
model coupled processes of different temporal and spatial resolutions and scales, and their flexibility to incorporate and / or couple to
models based on other approaches (such
as agent - based
modeling, stochastic
modeling, etc.) render them
as a versatile and efficient tool to
model coupled Earth — Human
Systems [190,191,19
Systems [190,191,192,193].
Therapeutic interventions with infants and families (including neurodevelopmental
models of intervention, dyadic and family
systems psychotherapies, such
as child - parent psychotherapy, parent - child
interaction therapy, DIR / Floortime; therapeutic use of videotape with families, Early Start Denver
Model, and more)
In humans, both the HPA
system and the autonomic nervous
system show developmental changes in infancy, with the HPA axis becoming organized between 2 and 6 months of age and the autonomic nervous
system demonstrating relative stability by 6 to 12 months of age.63 The HPA axis in particular has been shown to be highly responsive to child - caregiver
interactions, with sensitive caregiving programming the HPA axis to become an effective physiological regulator of stress and insensitive caregiving promoting hyperreactive or hyporeactive HPA
systems.17 Several animal
models as well
as human studies also support the connection between caregiver experiences in early postnatal life and alterations of autonomic nervous
system balance.63 - 65 Furthermore, children who have a history of sensitive caregiving are more likely to demonstrate optimal affective and behavioral strategies for coping with stress.66, 67 Therefore, children with histories of supportive, sensitive caregiving in early development may be better able to self - regulate their physiological, affective, and behavioral responses to environmental stressors and, consequently, less likely to manifest disturbed HPA and autonomic reactivity that put them at risk for stress - related illnesses such
as asthma.
It is a systemic couple's therapy, based upon the sequential, time - series, and mathematical
modeling of actual
interaction patterns that describe the relationship
as a
system.