Sentences with phrase «interactions on connectivity»

Not exact matches

To understand the selection mechanism behind mutations, network - based studies were used to estimate the importance of a mutated protein compared to non-mutated ones in signalling and protein — protein interaction networks.10, 11,12,13 Proteins mutated in cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets themselves.

In what the company calls a «grassroots, democratized education,» its social media hub offers myriad ways of connectivity, including: real interaction with real investors and building relationships through social media; asking questions on the site's forums and picking up knowledge and skills via the podcast; analyzing deals using property analysis calculators and printing reports to lenders and partners; and advertising in the marketplace and doing business in a particular community.

Our ability to deliver a «one - stop shop» service is founded on the connectivity and interaction between our labor and employment lawyers.

No touch interaction, very few pre-loaded apps with no easy way to add more, a pretty dreadful 2MP camera in tow, limited 3G connectivity, though on the bright side, all the drawbacks and blasts from the past help the battery supposedly last up to 22 days -LRB-!!!)