Sentences with phrase «interim analysis of»

The Data Monitoring and Ethics Committee met in July 2013 to review the safety of family therapy in a formal interim analysis of the primary endpoint, at which point no concerns were raised, and it was recommended that SHIFT continue to recruit the full sample.

Four studies were excluded because assignment to treatment was not random, 16 — 19 one because it was an interim analysis of an ongoing study, 20 and 11 because they involved children with depressive symptoms and not depressive disorder.21 — 31 This left six randomised trials of cognitive behaviour therapy for depressive disorder in young people.32 — 37 Two of the trials were conducted by the same research group 32 34 but it was clear from the trial descriptions that they were based on different samples.

An interim analysis of the 1020 participants recruited through December 2001 was conducted in July 2002 by an outside consultant.

The FDA's announcement is based on a five - year interim analysis of data gathered during an ongoing ten - year study.

An interim analysis of data received as of September 2017 showed that:

Limitations of this study include that it is an open - label study and the results are from a planned interim analysis of 10 of 17 enrolled infants (7 patients with 2 SMN2 copies and 3 with 3 SMN2 copies) who met the treatment duration criterion at the time of the interim analysis.1

In the interim analysis of this ongoing multiple - dose Phase 1b / 2a study, children with Type II or Type III SMA were dosed intrathecally with 3 mg, 6 mg or 9 mg of ISIS - SMNRx.

Synergen, a biotechnology company based in Boulder, Colorado, stopped the trial involving 700 patients when interim analysis of data showed that the drug, called Antril, was not working.

Interim analysis of a trial to protect against the deadly disease has been shown to, thus far, be successful.

Healthy adults mounted strong immune responses after receiving an investigational whole inactivated Zika virus vaccine, according to interim analyses of three Phase 1, placebo - controlled, double - blind trials conducted at Beth Israel Deaconess Medical Center (BIDMC), Walter Reed Army Institute of Research (WRAIR), and Saint Louis University School of Medicine.

The ERA - Interim analyses of soil moisture are included in the monthly summaries to provide a qualitative picture of major anomalies and to show the consistency with other variables.

The ERA - Interim analyses of soil moisture are included here to provide a qualitative picture of major anomalies and to show the consistency with other variables.

Not exact matches

said they will discontinue a late - stage trial of their experimental lung cancer drug after an interim analysis showed it would not meet the main goal of improving overall survival.

We're always open to evidence that would change our analysis of very long - term growth prospects for the U.S. economy, but that evidence evolves slowly enough that we could easily see another complete bull - bear cycle in the interim.

This interim analysis included 60 patients, with an average age of 68 years.

The U.S. study testing the long - term benefits and risks of hormone replacement therapy (HRT) was halted after an interim analysis found that the drugs — a combination of estrogen and progestin — increased the risk of breast cancer, stroke, and heart disease, and that those risks outweighed reduced risks of colorectal cancer and bone fractures (ScienceNOW, 9 July).

The interim analysis found a median progression - free survival rate of 9.7 months with consolidative radiation therapy followed by chemotherapy, versus 3.5 months for maintenance chemotherapy alone (p = 0.01; Hazard Ratio (HR) = 0.304, 95 % CI 0.113 - 0.815).

The trial, named PREVAIL, was concluded early, after a planned interim analysis, because of overwhelming response to the treatment.

In the lower - dose otamixaban group, discontinued by the data monitoring committee for futility based on the interim analysis, the rate of the primary outcome at day 7 was 6.3 percent.

But an interim analysis presented today by Foy and Dabiré at the annual meeting of the American Society of Tropical Medicine and Hygiene suggests that the drug is already having an impact.

A recent press release from Auspex Pharmaceuticals reported on an interim analysis from their ongoing ARC - HD trial that switching from tetrabenazine (Xenazine) to SD - 109, resulted in equal control of chorea in Huntington's disease.

NEWARK, Calif., May 31, 2016 (GLOBE NEWSWIRE)-- StemCells, Inc. (NASDAQ: STEM)(the «Company») today announced its decision to terminate the Company's Phase II Pathway Study in spinal cord injury following an in - depth review of data from the study and after obtaining the concurrence of the study's Interim Analysis Data Monitoring Committee (the «IA - DMC»).

Here we present an analysis of daily global fire weather trends from 1979 to 2013 based on three sub-daily global meteorological data sets (the National Center for Environmental Prediction (NCEP) Reanalysis, NCEP - DOE Reanalysis II and the European Centre for Medium - Range Weather Forecasts (ECMWF) Interim Reanalysis) 35,36,37 between ∼ 0.75 ° and 2.0 ° grid cell resolution.

A planned interim efficacy analysis was conducted based on 82 patients who completed at least 183 days of treatment, withdrew from the study, or died.

All patients treated with SPINRAZA who were alive at the time of the interim efficacy analysis either maintained or improved their HINE Section 2 scores.1

Gail Forrest, PhD, Interim Director of Human Performance and Movement Analysis Research at Kessler Foundation, and Steven Kirshblum, MD, Medical Director and Director of Spinal Cord Injury Rehabilitation at Kessler Institute for Rehabilitation, will lead a collaborative team for the investigational study.

A prospective study on the natural history of patients with profound combined immunodeficiency (P - CID): an interim analysis.

The team recommended the district improve its collection and analysis of interim student performance data, establish and enforce expectations for student learning and classroom assessment, and ask principals to consistently monitor curriculum delivery and differentiation.

Prior to joining UEI, Palmer - Klein served as a leader of the University YES Academy in Detroit, MI, supervising 14 teachers, designing and leading professional development, facilitating the student discipline system, and managing all interim assessment implementation, data collection, and analysis.

Democracy Prep utilizes a sophisticated feedback loop of frequent data collection and analysis including a network - wide dashboard tool, interim assessments, and comparative academic measures to drive effective instruction and decision - making.

Interim County Supt, Dewan, dismisses Alum Rock's 32 page Rocketship analysis with one & only one sentence: «Staff found no indicators of an unsound educational program».

She suggested the government could consider setting an interim target of 70 per cent of pupils sitting the EBacc but Datalab's analysis found only 42 per cent of schools could meet even that smaller target.

On January 16, the Office of the State Superintendent released an interim report, Analysis of Attendance and Graduation Outcomes at Public High Schools in DC.

Things are improving — so we are told and indeed your analysis of the figures confirms this and it should be further confirmed when the interims come out in a couple of months.

Additionally, safety reviews and interim analyses were planned as part of the EPIC Study, specifically, to monitor the safety of the study.

Here's a link to the analysis, The Interim Report on Causes of the Deepwater Horizon Oil Rig Blowout and Ways to Prevent Such Events and here's the disturbing core statement from the academy's summary: Read more...

A scientific evaluation of precipitation and surface relative humidity from ERA - Interim including comparisons with several other datasets was published for the first 20 years of completed analyses, covering 1989 to 2008.

In 2011, the Nongovernmental Panel on Climate Change (NIPCC) published Climate Change Reconsidered: 2011 Interim Report, a 400 - page report containing summaries and analysis of scientific research published since the original 2009 edition of Climate Change Reconsidered.

The new satellite Qa10 are used in combination with the newly reprocessed QuikSCAT V3, the latest version of sea surface temperature (SST) analyses, and with 10m air temperature estimated from the European Centre for Medium Weather Forecasts (ECMWF) re-analyses (ERA Interim).

To support analysis and monitoring of climate change, CDS users need access to state - of - the - art Climate Data Records (CDRs) and Interim Climate Data Records (ICDRs) for a variety of ECVs.

This does not mean the scientists should have to provide every single piece of interim analysis products like the deniers are currently hassling the community for — that is aimed at harassment not science transparency.

Doğan Gültutan - Review and Analysis of Interim Measures Available to Foreign Arbitrators in Turkey

although the EAT was unanimous in its approach to the legal analysis of «likely», one of its members was of the view that the chairman's assessment of the evidence was perverse (1075G), and accordingly that an order for interim relief ought to have been made.

However the advocate's task can be readily separated from the cost of routine legal work — document analysis and organization, interim motions, legal research, routine correspondence and scheduling.

(3) On interim support applications the court does not embark on an in - depth analysis of the parties» circumstances which is better left to trial.

On appeal, the appellate Court will embark upon a case by case analysis to determine whether the interim decision is likely to have a direct bearing on a fundamental trial issue; this is the standard of review.

The attached «toolkit» provides standardized forms, precedents, and checklists to make analysis of judicial interim release issues more effective, and to help maximize the efficient use of time while concurrently reducing or eliminating unnecessary use of court time.

Interim Spousal Support No Entitlement Lawyers argue that although interim support hearings do not involve as stringent an analysis of entitlement as a trial would, some evidence of entitlement...... Read FuInterim Spousal Support No Entitlement Lawyers argue that although interim support hearings do not involve as stringent an analysis of entitlement as a trial would, some evidence of entitlement...... Read Fuinterim support hearings do not involve as stringent an analysis of entitlement as a trial would, some evidence of entitlement...... Read Full Post

Although the analysis of such issues is not wholly clear, it is very clear that claimants should include evidence about the surrounding circumstances to enhance the chances of obtaining interim injunctions.

Served as Interim Branch Manager after only four months - maintained monthly reports, generated projective sales growth analysis; utilized my strong rapport building skills and professionalism to assure current clients of seamless service during our management transition.