Sentences with phrase «intervention trial design»

Thanks to the crossover intervention trial design, the researchers could control most of the potential confounders, such as population characteristics or past medical history.

The 40 - day physical activity study was a randomized intervention trial designed to increase physical activity of insufficiently active adults.

He also conducted an intervention trial designed to improve treatment attendance in this population.

Not exact matches

Our study illustrates that a randomized intervention trial with good socioeconomic information can help assess interventions designed to improve population health not only by examining the intervention effects on primary outcomes but also by evaluating the intervention's impact on socioeconomic inequalities.

Trials are needed that examine interventions designed specifically for women with multiples and delivered by people with training about how to overcome the particular challenges of breastfeeding more than one infant.

The objectives of this critical review are to identify and evaluate U.S. - based randomized trials evaluating breastfeeding interventions targeting minorities and highlight promising public health approaches designed to minimize breastfeeding disparities.

Legacy was developed by CDC in collaboration with the University of Miami, UCLA, and RTI International, and designed as a randomized controlled trial to test the idea that the Legacy intervention during early childhood might improve children's development.

We excluded a further 13 trials as the intervention was not designed to support continued breastfeeding; these studies examined more general interventions in the postnatal period (Ball 2011; Barlow 2006; Barnet 2002; Black 2001; Gagnon 1997; MacArthur 2002; Peterson 2002; Pollard 2011; Ratner 1999; Rush 1991; Serrano 2010; Thomson 2009; Wiggins 2005); a further trial by Baqui 2008 focused on breastfeeding initiation only, rather than on postnatal support to encourage continuation.

«The current landscape of stem cell tourism should prompt a re-evaluation of current approaches to study cell - based interventions with respect to the design, initiation and conduct of U.S. clinical trials,» the authors wrote.

«This will require discussions about alternative approaches to the design and conduct of clinical trials as well as to how interventions are approved by the Food and Drug Administration.»

In 1982 results came in from the Multiple Risk Factors Intervention Trial, which was designed to reduce the risk of coronary heart disease by counseling an experimental group to stop smoking, lower their blood pressure and cut back on saturated fat.

Innovative clinical trial approaches that have proven successful in other disease areas such as oncology (e.g., platform trials, umbrella and basket designs) might be employed with stratification of subjects by AT (N) profile, enabling a data - driven approach to identify the biological stage of disease in which an intervention has maximal treatment effects.

John DeLuca, PhD, VP of Research & Training chairs Workshop 6: Cognitive Rehabilitation in MS. Dr. DeLuca discusses assessment of cognitive problems and introduces common evidence - based techniques for improving cognitive functioning in persons with MS. Nancy Chiaravalloti, PhD, director of Neuropsychology & Neuroscience Research, presents two recent double - blind, placebo - controlled, randomized control trials of behavioral interventions designed to specifically improve learning and memory in persons with MS. Yael Goverover, PhD, OT, focuses on techniques to improve learning and memory, with a specific emphasis on improving everyday functional activity.

The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRtrial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRTrial (SPRINT).

In addition, randomized controlled trials proving sex - specific effects by adequately designed interventions are widely missing.

In several clinical trials of interventions designed to lower plasma cholesterol, reductions in coronary heart disease mortality have been offset by an unexplained rise in suicides and other violent deaths

In fact, Morgan, Palinkas, Barrett - Connor, and Winged (1993) articulate this with, «In several clinical trials of interventions designed to lower plasma cholesterol, reductions in coronary heart disease mortality have been offset by an unexplained rise in suicides and other violent deaths» (p. 75).

PREMIER — a trial of lifestyle interventions for blood pressure control: intervention design and rationale.

If someone wants to show that, he should design a randomized controlled trial in which the control and intervention group have the EXACT SAME diet except for the animal food, and no other lifestyle changes should be performed.

Three trials were weight - loss interventions designed to reduce total caloric intake by 30 % — 35 %.

Because we used a randomized controlled trial design, we were able to establish convincingly that our intervention was not only the cause of the educational gains; importantly, the program was also inexpensive.4

She has partnered with institutions around the country to help them base their decisions on data, incorporate predictive analytics, design interventions to solve process challenges, and test those interventions in randomized field trials or other rigorous research designs.

In collaboration with a student loan servicer and debt counseling non-profit, I design and implement a randomized control trial which evaluates several behavioral interventions aimed at lowering such psychological frictions.

This pragmatic trial was designed in accordance with the consolidated standards of reporting trials guidelines54 and was conducted by a research team independent of the programme, with an independent trial steering committee including chairman, parental representation and members with expertise in statistics; early years» intervention studies; and child psychiatry.

As with all interventions it will be extremely important to consider its efficacy and potential adverse effectsthrough properly designed randomised controlled trials before determining what, if any, place it has.

The project was designed as a randomised comparative trial of two interventions for youth and families, where the young person (12 to 25) presents with depression, anxiety, or alcohol and other drug (AOD) problems.

The block randomised design was chosen because it is a more practical design to use for trials of health promoting interventions delivered in groups.26 Only parents of children whose behaviour fell in the worst half of the distribution were invited to take part because of concerns about documenting change in population samples using instruments designed to identify and measure change in clinical populations.

Effects of an intervention designed to enhance romantic relationship excitement: A randomized - control trial.

She is the Principal Investigator of several NIH - funded trials of an intervention designed to increase positive emotion and improve psychological and physical well - being.

Group parenting programmes have been shown to have a positive impact on the mental health of children and parents in the short term.9 — 12 Positive results have been obtained from randomised controlled trials and other studies with parents of children with clinically defined behaviour disorders, 9,13,14 children at high risk of behaviour problems, 9,15 and to a lesser extent with normal populations.16, 17 They have also been obtained in trials of interventions for parents and children of different ages.18, 19 The number of trials carried out in the UK is small.13, 15,20,21 A recent systematic review concluded that these programmes are effective in the long term, 12 but most of the trials on which this review was based used a waiting list control design, and as a result outcome data are not reported on the control groups beyond 6 months.

Although this randomized controlled trial was designed to evaluate intervention outcomes on aggression, we take advantage of the experiment to test whether intervention that alters parenting and child risk factors for aggression also alters the cortisol response.

We designed the Bellevue Project for Early Language, Literacy, and Education Success (BELLE Project) to assess, through a randomized controlled trial (RCT), whether providing a primary care intervention before the beginning of ROR at 6 months and in addition to ROR after it has begun would result in an increased positive effect.

The randomized controlled trial was designed to evaluate intervention effects on parenting practices, child social competence, and aggression.

A multicentre randomised controlled trial with two arms of intervention: (active treatment) a parent and family program (BEST YMH) versus a (control treatment) supportive counselling condition designed to mirror treatment as usual for families (TAU).

To date, the immediate and lasting positive effects of quality care on language, cognitive development, and school achievement have been confirmed by converging findings from large, reasonably representative longitudinal studies and smaller, randomized trials with long - term follow - ups.1, 2,9 - 13 Contributors to this knowledge base include meta - analytic reviews of interventions and large longitudinal studies conducted in several countries.1, 2,14,15 Comprehensive meta - analyses now establish that effects of early care decline, but do not disappear, and when initial effects are large, long - term effects remain substantial.1, 2 Null findings in cognitive and social domains in a few studies may reasonably be attributed to the limitations inherent to their designs, samples, and measures.

She coordinates research - practice partnerships, designs interventions for testing in randomized trials, and conducts impact, implementation, and cost analyses for large - scale federal evaluations.

Of the nine intervention studies in 1987 — 1988, five were controlled experimental designs (two randomised controlled trials, three non-randomised controlled trials) and four were non-experimental designs (two single - group designs; two described only process variables or components of the intervention delivered rather than outcomes).

That intervention studies would predominantly use non-experimental designs, given the difficulties of undertaking experimental trials in this area.

Of the 31 intervention studies in 2001 — 2003, three were controlled experimental designs (randomised controlled trials) and 28 were non-experimental designs (15 longitudinal studies, two case — control studies, 11 single - group designs).

Of the 36 intervention studies in 1997 — 1998, nine (25 %) were controlled experimental designs (five randomised controlled trials, four non-randomised controlled trials) and 27 were non-experimental designs (four cohort or longitudinal studies, one case — control study, 22 single - group designs).

Intervention articles were classified as randomised controlled trial; non-randomised controlled trial; cohort / longitudinal analytic study; case — control study; single - group design (either pre — post measurement or post intervention measurement only, no control group)Intervention articles were classified as randomised controlled trial; non-randomised controlled trial; cohort / longitudinal analytic study; case — control study; single - group design (either pre — post measurement or post intervention measurement only, no control group)intervention measurement only, no control group); and other.

This is the first formal evaluation of adding a structured home intervention (HPS) to the IYP group - based programme and is a feasibility study to inform the design and implementation of a larger definitive randomised controlled trial.

The adaptation will be developed and tested first using single - case design methodology, and then via a randomized trial including 120 at - risk fathers to allow for a comparison of the MI - PCI intervention to a wait - list control group.

Fortunately, conducting randomized trials over the decades, intervention researchers have produced numerous manual - guided, evidence - based treatments (EBTs) for depression, anxiety, and conduct in youth.2 Unfortunately, these treatments have not been incorporated into most everyday clinical practice.3 - 5 A common view is that the complexity and comorbidity of many clinically referred youths, whose problems and treatment needs can shift during treatment, may pose problems for EBT protocols, which are typically designed for single or homogeneous clusters of disorders, developed and tested with recruited youths who differ from patients seen in everyday clinical practice, and involve a predetermined sequence of prescribed session contents, limiting their flexibility.3 - 8 Indeed, trials testing these protocols against usual care for young patients in clinical practice have produced mixed findings, with EBTs often failing to outperform usual care.7, 9

The randomized clinical trial uses a mixed design with three intervention conditions (one experimental condition and two control conditions) and five assessment points.

An exception to this criterion was applied to workplace health promotion interventions where controlled trials are rare; in this case other empirical study designs alongside an economic analysis were also eligible.

Design Two arm, single (assessor) blinded parallel randomised allocation trial of a group therapy intervention in addition to routine care, compared with routine care alone.