Sentences with phrase «intestinal cell damage»

Read the full study at «Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease»

Research reported by Columbia University Medical Center has stated that those without a formal celiac diagnosis can still experience a whole body immune response to wheat consumption related to a weakening of the intestinal barrier, as well as wheat causing intestinal cell damage.

Intestinal cell damage may also occur in people with gluten sensitivity (as with celiac disease).

Not exact matches

Moreover, she found, once the toxins are taken up by cells lining the mammalian gut, these sections become activated, setting in motion a chain of intracellular events that causes intestinal inflammation and tissue damage.

«Single gene encourages growth of intestinal stem cells, supporting «niche» cells, and cancer: Finding in mice could lead to new therapies for damaged organs, cancer.»

IGFBP3 binds to a receptor protein on colonic stem cells causing their death and, in turn, damaging the intestinal lining.»

The drug treatment and radiation cause damage to the epithelial cells, which form part of the intestinal mucosal layer.

The mice were found to have an abnormal microbiome, along with damaged junctions between the cells of the intestinal lining.

To find methods for stemming the tide of liver - damaging microbes, Schnabl and team tried experimentally bumping up copies of the REG3G gene in intestinal lining cells grown in the lab.

Since stem cells are also critical for regeneration in the intestine, therapies that target these pathways may further help to design new drugs that reduce side effects associated with chemotherapy, radiotherapy or other causes of intestinal damage.

Circulating levels of... a marker of intestinal epithelial cell damage, were significantly elevated in the affected individuals and correlated with the immune responses to microbial products...

In laboratory studies apple polyphenol extracts were found to prevent damage to human gastric epithelial (intestinal wall) cells.

When the intestinal lining becomes further damaged, even larger substances, such as disease - causing bacteria, undigested food particles, and toxins, pass directly through the damaged cells.

Glutamine provides fuel for the cells in the intestinal walls to regrow and repair damaged areas of your gut.

You can directly nourish intestinal cells with L - glutamine, an amino acid that rebuilds and repairs cellular damage.

When the immune system has been compromised, or when the normal lining of the gut becomes damaged, the yeast, instead of remaining within the intestinal tract where they belong, can metamorphose into its fungal form sending out rhizomes (roots) to penetrate the walls of the gut, opening it to the absorption of yeast cells, particles of cells, and the toxins these micro organisms produce enter the interior of the body and pass into the bloodstream.

The condition is autoimmune in nature, which means gluten doesn't cause the damage directly; instead, your immune system's reaction to the gluten protein spurs your white blood cells to mistakenly attack your small intestinal lining.

As the intestinal lining of the small bowel becomes more damaged over time, substances larger than particle size such as disease causing bacteria and fungus, potentially toxic molecules and undigested food particles pass through these weakened and «leaky» cell membranes.

AAEM pointed to numerous animal studies that showed oxidative stress, altered structure and function of the liver, intestinal damage, disruption of the immune system, increased cell growth and hundreds of alterations in gene expressions.

In the study, sulforaphane prevented damage to the cells that line the small intestine, which can lead to intestinal ulcers and infections.

Intestinal inflammation damages those villi cells and hurts your body's ability to produce the lactase enzyme, making it difficult to digest some forms of dairy.

Intestinal mucosal cells are replaced within 6 days; this means that there is a tremendous turnover of cells, even more so for people with conditions exhibiting damage to the gut lining.

For those suffering from lead or other heavy metal poisoning, a protective diet that avoids processed foods and emphasizes the central components of a nutrient - dense and antioxidant - rich WAPF - style diet is essential (see sidebar).21 Nutritional status shapes susceptibility to lead toxicity in important ways, affecting lead's intestinal absorption; its mobilization, distribution and retention in the body; and excretion.22 Because oxidative stress is a likely mechanism explaining some of lead's toxic actions, some investigators have begun to explore whether natural antioxidants and trace minerals may help mitigate lead - induced cell damage.17 Specifically, researchers in Spain found that administration of vitamins A, B6, C and E along with zinc modulated some of the negative effects of lead exposure in rat pups, confirming the influence of nutritional factors on health outcomes following lead exposure.17 Vitamin D also should be a major component of a protective diet.

This leaves the intestines and muscle cells vulnerable to oxidation damage, which can explain both the intestinal inflammation and the muscle wasting associated with Crohn's disease.

In an animal model, there was mitochondrial damage in the cells of the intestinal brush border within an hour of NSAID (indomethacin) administration.

Intestinal cells are sensitive to DNA damage, caused by environmental factors.

Nutrients are normally absorbed through the cells at the tip of the intestinal villi, however, when the intestine is damaged from inflammation, the villi are no longer healthy and in tact and are unable to properly absorb the available nutrients.

It is a parvo virus that causes its damage by attacking rapidly growing cells such as the intestinal tract, bone marrow, lymphatic system, and neurological system.

Onions, chives and garlic are extremely dangerous to pets and can cause gastro intestinal irritation and can lead to red cell damage.

Unfortunately, normal healthy cells can also be damaged or destroyed by the radiation, particularly actively dividing cells like those of the intestinal lining, bone marrow and immune system.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)

This chemical is also reported to cause cell membrane damage, which can cause irritation of the nervous system and intestinal tract.